Reactome | SUCLA2 [mitochondrial matrix]

SUCLA2 [mitochondrial matrix]

Stable Identifier

R-HSA-156624

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

Succinyl-CoA synthetase, betaA chain

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9P2R7 SUCLA2

Gene Names

SUCLA2

Chain

transit peptide:1-52, chain:53-463

Reference Genes

BioGPS Gene:8803 SUCLA2

COSMIC (genes):SUCLA2 SUCLA2

CTD Gene:8803 SUCLA2

dbSNP Gene:8803 SUCLA2

ENSEMBL:ENSG00000136143 SUCLA2

HGNC:11448 SUCLA2

KEGG Gene (Homo sapiens):8803 SUCLA2

Monarch:8803 SUCLA2

NCBI Gene:8803 SUCLA2

OMIM:603921 SUCLA2

UCSC:Q9P2R7 SUCLA2

Reference Transcript

RefSeq:NM_003850.2 SUCLA2

Other Identifiers

11748619_a_at

11748620_x_at

11755266_x_at

11755492_a_at

11759519_a_at

16778956

16778959

202930_s_at

2544609

2901605

3513309

3513310

3513323

3513324

3513325

3513326

3513327

3513328

3513332

3513333

3513334

3513336

3513340

3513343

3513347

3513348

3513351

3513352

3513353

3513356

3513357

3513372

3513373

3513377

3513379

3513381

40893_at

7971541

84409_i_at

8803

A_21_P0011228

A_23_P117157

GE683287

GO:0000166

GO:0000287

GO:0003674

GO:0003824

GO:0004775

GO:0004776

GO:0005515

GO:0005524

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005737

GO:0005739

GO:0005759

GO:0006091

GO:0006099

GO:0006104

GO:0006105

GO:0006781

GO:0006790

GO:0008150

GO:0009058

GO:0016874

GO:0032991

GO:0034641

GO:0042709

GO:0043167

GO:0043226

GO:0044281

GO:0046872

GO:0070062

HMNXSV003007310

HMNXSV003050089

ILMN_1660787

PH_hs_0010761

TC13000651.hg

TC13000652.hg

g11321582_3p_a_at

Participates

as a component of

SUCLA2:SUCLG1 [mitochondrial matrix] (Homo sapiens)

Inferred To

LSC2 [mitochondrial matrix] (Saccharomyces cerevisiae)

ScsbetaA [mitochondrial matrix] (Drosophila melanogaster)

SUCLA2 [mitochondrial matrix] (Gallus gallus)

SUCLA2 [mitochondrial matrix] (Plasmodium falciparum)

SUCLA2 [mitochondrial matrix] (Schizosaccharomyces pombe)

scsC [mitochondrial matrix] (Dictyostelium discoideum)

sucla2 [mitochondrial matrix] (Danio rerio)

sucla2 [mitochondrial matrix] (Xenopus tropicalis)

suca-1 [mitochondrial matrix] (Caenorhabditis elegans)

Sucla2 [mitochondrial matrix] (Mus musculus)

Sucla2 [mitochondrial matrix] (Rattus norvegicus)

Cross References

RefSeq

NP_003841.1

OpenTargets

ENSG00000136143

HPA

ENSG00000136143-SUCLA2

GeneCards

Q9P2R7

Ensembl

ENSP00000494987, ENST00000643584, ENST00000646932, ENSG00000136143, ENSP00000494360

PRO

Q9P2R7

Pharos - Targets

Q9P2R7

GlyGen

Q9P2R7

Orphanet

15568

HMDB Protein

HMDBP00971

PDB

6G4Q

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96CV9 OPTN	4	OPTN [Golgi membrane] (R-HSA-2161111) OPTN [recycling endosome membrane] (R-HSA-8854141) p-S177-OPTN [cytosol] (R-HSA-2562525) p-S177-OPTN [nucleoplasm] (R-HSA-2562595)	0.556	3
UniProt:Q9UBN6 TNFRSF10D	1	TNFRSF10D [plasma membrane] (R-HSA-5633374)	0.556	3
UniProt:Q15436 SEC23A	4	SEC23A [ER to Golgi transport vesicle membrane] (R-HSA-204024) p-S742,T747 SEC23A [cytosol] (R-HSA-5685740) SEC23A [cytosol] (R-HSA-203972) SEC23A [endoplasmic reticulum membrane] (R-HSA-203976)	0.556	3