BfrA stores iron

Stable Identifier
R-HSA-1562604
Type
Reaction [transition]
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Compartment
cytosol
ReviewStatus
5/5
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BfrA stores iron
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Mtb bacterioferritin BfrA oxidises Fe2+ to Fe3+, migrates them to its centre, and collects thousands of them as FeO(OH) in the central mineral core from which they can be later remobilised (Reddy et al. 2012).

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Output
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as an event of
Catalyst Activity

ferroxidase activity of BfrA complex [cytosol]

Physical Entity
BfrA complex [cytosol] (Mycobacterium tuberculosis)
Activity
ferroxidase activity (GO:0004322)
Disease
Name Identifier Synonyms
tuberculosis DOID:399 tuberculous abscess, Tuberculoma (finding), tuberculoma
Cross References
Rhea
Authored
Stephan, R  (2011-01-10)
Reviewed
Warner, D  (2012-04-30)
Created
Jassal, B  (2011-09-05)
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