Nitrogen dioxide is reduced to NO by F420

Stable Identifier
R-HSA-1500761
Type
Reaction [transition]
Species
Homo sapiens
Related Species
Mycobacterium tuberculosis
Compartment
cytosol
ReviewStatus
5/5
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Nitrogen dioxide is reduced to NO by F420
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The archaeal cofactor F420 reduces toxic nitrogen dioxide that can be produced when NO and oxygen combine. F420 itself is reduced by the enzyme Fgd (Purwantini & Mukhopadyay 2008).
Literature References
PubMed ID Title Journal Year
19325122 Conversion of NO2 to NO by reduced coenzyme F420 protects mycobacteria from nitrosative damage

Mukhopadhyay, B, Purwantini, E

Proc Natl Acad Sci U S A 2009
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Output
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Disease
Name Identifier Synonyms
tuberculosis DOID:399 tuberculous abscess, Tuberculoma (finding), tuberculoma
Authored
Stephan, R  (2011-01-10)
Reviewed
Warner, D  (2012-04-30)
Created
Jassal, B  (2011-08-22)
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