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PLA2G2A [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-1498802
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
Group IIA phospholipase A2, Non-pancreatic secretory phospholipase A2
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Phospholipid metabolism (Homo sapiens)
Glycerophospholipid biosynthesis (Homo sapiens)
Acyl chain remodelling of PC (Homo sapiens)
PC is hydrolyzed to 1-acyl LPC by PLA2[6] (Homo sapiens)
PLA2(6) [endoplasmic reticulum membrane] (Homo sapiens)
PLA2G2A:Ca2+ [endoplasmic reticulum membrane] (Homo sapiens)
PLA2G2A [endoplasmic reticulum membrane] (Homo sapiens)
Acyl chain remodelling of PE (Homo sapiens)
PE is hydrolyzed to 1-acyl LPE by PLA2[3] (Homo sapiens)
PLA2(3) [endoplasmic reticulum membrane] (Homo sapiens)
PLA2G2A:Ca2+ [endoplasmic reticulum membrane] (Homo sapiens)
PLA2G2A [endoplasmic reticulum membrane] (Homo sapiens)
Acyl chain remodelling of PG (Homo sapiens)
PG is hydrolyzed to 1-acyl LPG by PLA2G2A (Homo sapiens)
PLA2G2A:Ca2+ [endoplasmic reticulum membrane] (Homo sapiens)
PLA2G2A [endoplasmic reticulum membrane] (Homo sapiens)
Acyl chain remodelling of PI (Homo sapiens)
PI is hydrolyzed to 1-acyl LPI by PLA2[12] (Homo sapiens)
PLA2(12) [endoplasmic reticulum membrane] (Homo sapiens)
PLA2G2A:Ca2+ [endoplasmic reticulum membrane] (Homo sapiens)
PLA2G2A [endoplasmic reticulum membrane] (Homo sapiens)
Acyl chain remodelling of PS (Homo sapiens)
PS is hydrolyzed to 1-acyl LPS by PLA2G2A (Homo sapiens)
PLA2G2A:Ca2+ [endoplasmic reticulum membrane] (Homo sapiens)
PLA2G2A [endoplasmic reticulum membrane] (Homo sapiens)
Synthesis of PA (Homo sapiens)
PA is hydrolysed to 1-acyl LPA by PLA2G2A (Homo sapiens)
PLA2G2A:Ca2+ [endoplasmic reticulum membrane] (Homo sapiens)
PLA2G2A [endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P14555 PLA2G2A
Gene Names
PLA2G2A, PLA2B, PLA2L, RASF-A
Chain
signal peptide:1-20, chain:21-144
Reference Genes
BioGPS Gene:5320 PLA2G2A
COSMIC (genes):PLA2G2A PLA2G2A
CTD Gene:5320 PLA2G2A
dbSNP Gene:5320 PLA2G2A
ENSEMBL:ENSG00000188257 PLA2G2A
HGNC:9031 PLA2G2A
KEGG:hsa:5320 PLA2G2A
Monarch:5320 PLA2G2A
NCBI Gene:5320 PLA2G2A
OMIM:172411 PLA2G2A
UCSC:P14555 PLA2G2A
Reference Transcript
RefSeq:NM_001161729.1 PLA2G2A
RefSeq:NM_001161728.1 PLA2G2A
RefSeq:NM_001161727.1 PLA2G2A
RefSeq:NM_000300.3 PLA2G2A
Other Identifiers
11718416_a_at
11754033_a_at
11757057_x_at
16682771
203649_PM_s_at
203649_s_at
2400026
2400028
2400029
2400030
2400032
2400033
2400034
2400035
2400036
2400037
2400038
2400039
2400040
2400041
2400042
2400043
2400044
2400046
37017_at
5320
614_at
7913216
A_23_P321949
GE57869
GO:0003824
GO:0004623
GO:0005509
GO:0005543
GO:0005576
GO:0005615
GO:0005739
GO:0005741
GO:0005783
GO:0005789
GO:0005886
GO:0006629
GO:0006644
GO:0006954
GO:0008289
GO:0010744
GO:0016042
GO:0016787
GO:0030141
GO:0031410
GO:0031640
GO:0034374
GO:0036335
GO:0042130
GO:0042742
GO:0043226
GO:0046337
GO:0046470
GO:0046473
GO:0046872
GO:0047498
GO:0048471
GO:0050482
GO:0050729
GO:0050830
GO:0070062
GO:0070374
GO:0098542
GO:1902563
HMNXSV003039090
ILMN_1740586
M22430_at
TC01002307.hg
g4505848_3p_s_at
Participates
as a component of
PLA2G2A:Ca2+ [endoplasmic reticulum membrane] (Homo sapiens)
Other forms of this molecule
PLA2G2A [extracellular region]
Inferred To
Homologues of PLA2G2A [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Homologues of PLA2G2A [endoplasmic reticulum membrane]
(Xenopus tropicalis)
PLA2G2A [endoplasmic reticulum membrane]
(Bos taurus)
PLA2G2A [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
PLA2G2A [endoplasmic reticulum membrane]
(Drosophila melanogaster)
PLA2G2A [endoplasmic reticulum membrane]
(Gallus gallus)
PLA2G2A [endoplasmic reticulum membrane]
(Mus musculus)
PLA2G2A [endoplasmic reticulum membrane]
(Rattus norvegicus)
PLA2G2A [endoplasmic reticulum membrane]
(Sus scrofa)
PLA2G2A [endoplasmic reticulum membrane]
(Xenopus tropicalis)
Cross References
RefSeq
NP_000291.1
,
NP_001155199.1
,
NP_001155201.1
,
NP_001155200.1
Guide to Pharmacology - Targets
1417
OpenTargets
ENSG00000188257
ENSEMBL
ENSP00000364252
,
ENST00000482011
,
ENSP00000504762
,
ENSP00000383364
,
ENST00000375111
,
ENST00000400520
ZINC - Substances
PA2GA_HUMAN
ZINC - Biogenic
PA2GA_HUMAN
ZINC target
P14555
PRO
P14555
GlyGen
P14555
PDB
3U8I
,
1J1A
,
5G3N
,
1DCY
,
3U8D
,
1POE
,
1POD
,
1BBC
,
1KVO
,
3U8H
,
3U8B
,
1DB5
,
1DB4
,
1AYP
,
1N29
,
1N28
,
1KQU
ZINC - Investigational
PA2GA_HUMAN
HPA
ENSG00000188257-PLA2G2A
Pharos - Targets
P14555
ZINC - Predictions - Purchasable
PA2GA_HUMAN
HMDB Protein
HMDBP00072
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