Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
PLA2G4D [cytosol]
Stable Identifier
R-HSA-1498792
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Cytosolic phospholipase A2 delta, cPLA2-delta, Phospholipase A2 group IVD
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Phospholipid metabolism (Homo sapiens)
Glycerophospholipid biosynthesis (Homo sapiens)
Acyl chain remodelling of PC (Homo sapiens)
PC is hydrolysed to 2-acyl LPC by PLA2[7] (Homo sapiens)
PLA2(7) [cytosol] (Homo sapiens)
PLA2G4D [cytosol] (Homo sapiens)
PC is hydrolyzed to 1-acyl LPC by PLA2[5] (Homo sapiens)
PLA2(5) [cytosol] (Homo sapiens)
PLA2G4D [cytosol] (Homo sapiens)
Acyl chain remodelling of PE (Homo sapiens)
PE is hydrolyzed to 1-acyl LPE by PLA2[2] (Homo sapiens)
PLA2(2) [cytosol] (Homo sapiens)
PLA2G4D [cytosol] (Homo sapiens)
PE is hydrolyzed to 2-acyl LPE by PLA2[4] (Homo sapiens)
PLA2(4) [cytosol] (Homo sapiens)
PLA2G4D [cytosol] (Homo sapiens)
Acyl chain remodelling of PG (Homo sapiens)
PG is hydrolyzed to 1-acyl LPG by PLA2[1] (Homo sapiens)
PLA2(1) [cytosol] (Homo sapiens)
PLA2G4D [cytosol] (Homo sapiens)
PG is hydrolyzed to 2-acyl LPG by PLA2[14] (Homo sapiens)
PLA2(14) [cytosol] (Homo sapiens)
PLA2G4D [cytosol] (Homo sapiens)
Acyl chain remodelling of PI (Homo sapiens)
PI is hydrolyzed to 1-acyl LPI by PLA2[11] (Homo sapiens)
PLA2(11) [cytosol] (Homo sapiens)
PLA2G4D [cytosol] (Homo sapiens)
PI is hydrolyzed to 2-acyl LPI by PLA2[13] (Homo sapiens)
PLA2(13) [cytosol] (Homo sapiens)
PLA2G4D [cytosol] (Homo sapiens)
Acyl chain remodelling of PS (Homo sapiens)
PS is hydrolyzed to 1-acyl LPS by PLA2[9] (Homo sapiens)
PLA2(9) [cytosol] (Homo sapiens)
PLA2G4D [cytosol] (Homo sapiens)
PS is hydrolyzed to 2-acyl LPS by PLA2[10] (Homo sapiens)
PLA2(10) [cytosol] (Homo sapiens)
PLA2G4D [cytosol] (Homo sapiens)
Hydrolysis of LPC (Homo sapiens)
1-acyl LPC is hydrolyzed to GPCho by PLA2[8] (Homo sapiens)
PLA2(8) [cytosol] (Homo sapiens)
PLA2G4D [cytosol] (Homo sapiens)
2-acyl LPC is hydrolyzed to GPCho by PLA2[8] (Homo sapiens)
PLA2(8) [cytosol] (Homo sapiens)
PLA2G4D [cytosol] (Homo sapiens)
Synthesis of PA (Homo sapiens)
PA is hydrolysed to 1-acyl LPA by PLA2[1] (Homo sapiens)
PLA2(1) [cytosol] (Homo sapiens)
PLA2G4D [cytosol] (Homo sapiens)
PA is hydrolyzed to 1-acyl LPA by PLA2[1] (OM) (Homo sapiens)
PLA2(1) [cytosol] (Homo sapiens)
PLA2G4D [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q86XP0 PLA2G4D
Gene Names
PLA2G4D
Chain
chain:1-818
Reference Genes
BioGPS Gene:283748 PLA2G4D
COSMIC (genes):PLA2G4D PLA2G4D
CTD Gene:283748 PLA2G4D
dbSNP Gene:283748 PLA2G4D
ENSEMBL:ENSG00000159337 PLA2G4D
HGNC:30038 PLA2G4D
KEGG:hsa:283748 PLA2G4D
Monarch:283748 PLA2G4D
NCBI Gene:283748 PLA2G4D
OMIM:612864 PLA2G4D
UCSC:Q86XP0 PLA2G4D
Reference Transcript
RefSeq:NM_178034.3 PLA2G4D
Other Identifiers
11738277_a_at
16807797
283748
3620381
3620382
3620383
3620384
3620385
3620386
3620387
3620388
3620389
3620390
3620391
3620392
3620393
3620394
3620395
3620398
3620399
3620400
3620401
3620402
3620403
3620404
3620405
3620406
3620407
3620415
3620416
7987792
A_33_P3361611
GE577920
GO:0003824
GO:0004620
GO:0004623
GO:0005509
GO:0005544
GO:0005737
GO:0005829
GO:0006629
GO:0006631
GO:0006650
GO:0008289
GO:0008970
GO:0009395
GO:0016020
GO:0016042
GO:0016787
GO:0036148
GO:0036149
GO:0046475
GO:0046872
GO:0047498
GO:0052689
HMNXSV003015352
ILMN_1662351
ILMN_2217270
PH_hs_0028284
TC15001259.hg
Participates
as a member of
PLA2(14) [cytosol] (Homo sapiens)
PLA2(9) [cytosol] (Homo sapiens)
PLA2(2) [cytosol] (Homo sapiens)
PLA2(10) [cytosol] (Homo sapiens)
PLA2(5) [cytosol] (Homo sapiens)
PLA2(11) [cytosol] (Homo sapiens)
PLA2(8) [cytosol] (Homo sapiens)
PLA2(1) [cytosol] (Homo sapiens)
PLA2(4) [cytosol] (Homo sapiens)
PLA2(7) [cytosol] (Homo sapiens)
PLA2(13) [cytosol] (Homo sapiens)
Other forms of this molecule
PLA2G4D [mitochondrial inner membrane]
Inferred To
PLB1 [cytosol]
(Saccharomyces cerevisiae)
PLA2G4D [cytosol]
(Bos taurus)
PLA2G4D [cytosol]
(Canis familiaris)
PLA2G4D [cytosol]
(Gallus gallus)
PLA2G4D [cytosol]
(Mus musculus)
PLA2G4D [cytosol]
(Schizosaccharomyces pombe)
PLA2G4D [cytosol]
(Sus scrofa)
Pla2g4d [cytosol]
(Rattus norvegicus)
Homologues of PLA2G4D [cytosol]
(Saccharomyces cerevisiae)
Homologues of PLA2G4D [cytosol]
(Schizosaccharomyces pombe)
SPO1 [cytosol]
(Saccharomyces cerevisiae)
plb1 [cytosol]
(Schizosaccharomyces pombe)
PLB3 [cytosol]
(Saccharomyces cerevisiae)
PLB2 [cytosol]
(Saccharomyces cerevisiae)
Cross References
RefSeq
NP_828848.3
Guide to Pharmacology - Targets
1427
ENSEMBL
ENST00000290472
,
ENSP00000290472
OpenTargets
ENSG00000159337
HPA
ENSG00000159337-PLA2G4D
PRO
Q86XP0
Pharos - Targets
Q86XP0
HMDB Protein
HMDBP07863
PDB
5IZR
,
5IZ5
,
5IXC
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
