Reactome | LCLAT1 [endoplasmic reticulum membrane]

LCLAT1 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-1498783

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

AGPAT8, Lysocardiolipin acyltransferase 1, 1-acylglycerol-3-phosphate O-acyltransferase 8, ALCAT1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q6UWP7 LCLAT1

Gene Names

LCLAT1, AGPAT8, ALCAT1, LYCAT, UNQ1849/PRO3579

Chain

chain:1-414

Reference Genes

BioGPS Gene:253558 LCLAT1

COSMIC (genes):LCLAT1 LCLAT1

CTD Gene:253558 LCLAT1

dbSNP Gene:253558 LCLAT1

ENSEMBL:ENSG00000172954 LCLAT1

ENSEMBL_homo_sapiens_GENE:ENSG00000172954.14 LCLAT1

HGNC:26756 LCLAT1

KEGG Gene (Homo sapiens):253558 LCLAT1

Monarch:253558 LCLAT1

NCBI Gene:253558 LCLAT1

UCSC:Q6UWP7 LCLAT1

Reference Transcript

Other Identifiers

11722540_a_at

11728959_a_at

11750921_a_at

16878699

226996_PM_at

226996_at

2475730

2475734

2475735

2475742

2475744

2475748

2475750

2475763

2475764

2475769

2475770

2475771

2475772

2475773

2475774

2475775

253558

2910834

78505_at

8041212

A_14_P116827

A_14_P134912

A_14_P202079

A_24_P66337

A_32_P92505

A_33_P3349693

GE86857

GO:0003824

GO:0003841

GO:0005515

GO:0005783

GO:0005789

GO:0005829

GO:0006629

GO:0006654

GO:0008374

GO:0008654

GO:0012505

GO:0016020

GO:0016024

GO:0016740

GO:0016746

GO:0035965

GO:0036149

GO:0043226

HMNXSV003047577

HMNXSV003048060

Hs.14355.0.S1_3p_at

ILMN_1708081

ILMN_1724191

PH_hs_0001366

PH_hs_0031011

Participates

as a member of

AGPAT [endoplasmic reticulum membrane] (Homo sapiens)

Inferred To

CST26 [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)

LCLAT1 [endoplasmic reticulum membrane] (Bos taurus)

LCLAT1 [endoplasmic reticulum membrane] (Canis familiaris)

LCLAT1 [endoplasmic reticulum membrane] (Dictyostelium discoideum)

LCLAT1 [endoplasmic reticulum membrane] (Gallus gallus)

LCLAT1 [endoplasmic reticulum membrane] (Schizosaccharomyces pombe)

LCLAT1 [endoplasmic reticulum membrane] (Sus scrofa)

Lclat1 [endoplasmic reticulum membrane] (Mus musculus)

Lclat1 [endoplasmic reticulum membrane] (Rattus norvegicus)

acl-8 [endoplasmic reticulum membrane] (Caenorhabditis elegans)

lclat1 [endoplasmic reticulum membrane] (Danio rerio)

lclat1 [endoplasmic reticulum membrane] (Xenopus tropicalis)

Cross References

RefSeq

XP_016859235.1, NP_872357.2, XP_011531044.1, NP_001291374.1, NP_001002257.1, XP_005264302.1, XP_011531045.1, XP_011531043.1, XP_005264301.1

OpenTargets

ENSG00000172954

HPA

ENSG00000172954-LCLAT1

GeneCards

Q6UWP7

Ensembl

ENST00000309052, ENSP00000310551, ENST00000379509, ENSP00000368823, ENSG00000172954, ENSP00000368826, ENST00000319406

PRO

Q6UWP7

Pharos - Targets

Q6UWP7

HMDB Protein

HMDBP07309

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8TBB1 LNX1	1	LNX1 [cytosol] (R-HSA-8851641)	0.556	3
UniProt:Q9HD26 GOPC	3	GOPC [lysosomal membrane] (R-HSA-5627281) GOPC [plasma membrane] (R-HSA-5626572) GOPC [Golgi-associated vesicle membrane] (R-HSA-5627067)	0.556	3
UniProt:Q9NRD5 PICK1	2	PICK1 [endocytic vesicle membrane] (R-HSA-417017) PICK1 [plasma membrane] (R-HSA-416989)	0.556	3

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