Ferrous iron reduces the BH3 radical back to BH4

Stable Identifier
R-HSA-1497883
Type
Reaction [transition]
Species
Homo sapiens
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Heme iron from the oxygenase domain of eNOS can reduce the BH3 radical back to BH4, with itself being oxidised from the ferrous (Fe2+) back to the ferric (Fe3+) form (Berka et al. 2004).

Literature References
PubMed ID Title Journal Year
15476407 Redox function of tetrahydrobiopterin and effect of L-arginine on oxygen binding in endothelial nitric oxide synthase

Berka, V, Yeh, HC, Gao, D, Kiran, F, Tsai, AL

Biochemistry 2004
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