Ferrous iron reduces the BH3 radical back to BH4

Stable Identifier
R-HSA-1497883
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Ferrous iron reduces the BH3 radical back to BH4
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Heme iron from the oxygenase domain of eNOS can reduce the BH3 radical back to BH4, with itself being oxidised from the ferrous (Fe2+) back to the ferric (Fe3+) form (Berka et al. 2004).
Literature References
PubMed ID Title Journal Year
15476407 Redox function of tetrahydrobiopterin and effect of L-arginine on oxygen binding in endothelial nitric oxide synthase

Berka, V, Yeh, HC, Tsai, AL, Kiran, F, Gao, D

Biochemistry 2004
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Authored
Jassal, B  (2011-08-17)
Reviewed
D'Eustachio, P  (2011-08-23)
Created
Jassal, B  (2011-08-17)
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