DAG and IP3 signaling

Stable Identifier
R-HSA-1489509
Type
Pathway
Species
Homo sapiens
Compartment
cytosol, extracellular region, plasma membrane
ReviewStatus
5/5
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DAG and IP3 signaling
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This pathway describes the generation of DAG and IP3 by the PLCgamma-mediated hydrolysis of PIP2 and the subsequent downstream signaling events.

Literature References
PubMed ID Title Journal Year
16260143 Phospholipase C-gamma: diverse roles in receptor-mediated calcium signaling

Snyder, SH, Nikolaidis, N, van Rossum, DB, Gill, DL, Patterson, RL

Trends Biochem Sci 2005
Participants
Events
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as an event of
Orthologous Events
DAG and IP3 signaling (Bos taurus)
DAG and IP3 signaling (Caenorhabditis elegans)
DAG and IP3 signaling (Canis familiaris)
DAG and IP3 signaling (Danio rerio)
DAG and IP3 signaling (Dictyostelium discoideum)
DAG and IP3 signaling (Drosophila melanogaster)
DAG and IP3 signaling (Gallus gallus)
DAG and IP3 signaling (Mus musculus)
DAG and IP3 signaling (Plasmodium falciparum)
DAG and IP3 signaling (Rattus norvegicus)
DAG and IP3 signaling (Saccharomyces cerevisiae)
DAG and IP3 signaling (Schizosaccharomyces pombe)
DAG and IP3 signaling (Sus scrofa)
DAG and IP3 signaling (Xenopus tropicalis)
Cross References
BioModels Database
Authored
Nasi, S  (2006-10-10)
Annibali, D  (2006-10-10)
Reviewed
Greene, LA  (2007-11-08)
Created
Rothfels, K  (2011-08-15)
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