PCho is dephosphorylated to Cho by PHOSPHO1

Stable Identifier
R-HSA-1483159
Type
Reaction
Species
Homo sapiens
Compartment
cytosol
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PCho is dephosphorylated to Cho by PHOSPHO1
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In the cytosol, the phosphoethanolamine/phosphocholine phosphatase (PHOSPHO1) dephosphorylates phosphocholine (PCho) to choline (Cho) (Roberts et al. 2004).

Literature References
PubMed ID Title Journal Year
15175005 Human PHOSPHO1 exhibits high specific phosphoethanolamine and phosphocholine phosphatase activities

Sadler, PJ, Stewart, AJ, Roberts, SJ, Farquharson, C

Biochem J 2004
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Catalyst Activity

phosphocholine phosphatase activity of PHOSPHO1:Mg2+ [cytosol]

Physical Entity
PHOSPHO1:Mg2+ [cytosol] (Homo sapiens)
Activity
phosphocholine phosphatase activity (GO:0052731)
Orthologous Events
PCho is dephosphorylated to Cho by PHOSPHO1 (Bos taurus)
PCho is dephosphorylated to Cho by PHOSPHO1 (Canis familiaris)
PCho is dephosphorylated to Cho by PHOSPHO1 (Danio rerio)
PCho is dephosphorylated to Cho by PHOSPHO1 (Drosophila melanogaster)
PCho is dephosphorylated to Cho by PHOSPHO1 (Gallus gallus)
PCho is dephosphorylated to Cho by PHOSPHO1 (Mus musculus)
PCho is dephosphorylated to Cho by PHOSPHO1 (Rattus norvegicus)
PCho is dephosphorylated to Cho by PHOSPHO1 (Sus scrofa)
PCho is dephosphorylated to Cho by PHOSPHO1 (Xenopus tropicalis)
Authored
Williams, MG  (2011-09-14)
Created
Williams, MG  (2011-08-12)
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