Synthesis of PS

Stable Identifier
R-HSA-1483101
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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Synthesis of PS
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Phosphatidylserine (PS) is synthesized by facilitating the exchange of L-Serine (L-Ser) with the choline (Cho) head group in phosphatidylcholine (PC) and with the ethanolamine (ETA) head group in phosphatidylethanolamine (PE) (Saito et al. 1998, Tomohiro et al. 2009).
Literature References
PubMed ID Title Journal Year
9642289 Genetic evidence that phosphatidylserine synthase II catalyzes the conversion of phosphatidylethanolamine to phosphatidylserine in Chinese hamster ovary cells

Saito, K, Kuge, O, Nishijima, M

J Biol Chem 1998
19014349 Purification and characterization of human phosphatidylserine synthases 1 and 2

Kawabe, Y, Kitada, S, Tomohiro, S, Kuge, O, Kawaguti, A

Biochem J 2009
Participants
Events
Participates
as an event of
Event Information
Go Biological Process
phosphatidylserine biosynthetic process (0006659)
Orthologous Events
Synthesis of PS (Bos taurus)
Synthesis of PS (Caenorhabditis elegans)
Synthesis of PS (Canis familiaris)
Synthesis of PS (Danio rerio)
Synthesis of PS (Dictyostelium discoideum)
Synthesis of PS (Drosophila melanogaster)
Synthesis of PS (Gallus gallus)
Synthesis of PS (Mus musculus)
Synthesis of PS (Plasmodium falciparum)
Synthesis of PS (Rattus norvegicus)
Synthesis of PS (Sus scrofa)
Synthesis of PS (Xenopus tropicalis)
Authored
Williams, MG  (2011-09-14)
Reviewed
Wakelam, M  (2012-05-14)
Created
Williams, MG  (2011-08-12)
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