Synthesis of PS

Stable Identifier
R-HSA-1483101
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this pathway in the Pathway Browser

Phosphatidylserine (PS) is synthesized by facilitating the exchange of L-Serine (L-Ser) with the choline (Cho) head group in phosphatidylcholine (PC) and with the ethanolamine (ETA) head group in phosphatidylethanolamine (PE) (Saito et al. 1998, Tomohiro et al. 2009).

Literature References
PubMed ID Title Journal Year
19014349 Purification and characterization of human phosphatidylserine synthases 1 and 2

Tomohiro, S, Kawaguti, A, Kawabe, Y, Kitada, S, Kuge, O

Biochem J 2009
9642289 Genetic evidence that phosphatidylserine synthase II catalyzes the conversion of phosphatidylethanolamine to phosphatidylserine in Chinese hamster ovary cells

Saito, K, Nishijima, M, Kuge, O

J Biol Chem 1998
Participants
Participant Of
Event Information
Orthologous Events
Authored
Reviewed
Created