PCho and CTP are condensed to CDP-Cho by PCYT1 dimer

Stable Identifier
R-HSA-1483081
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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At the endoplasmic reticulum (ER) membrane, active membrane-bound choline-phosphate cytidylyltransferase A (PCYT1A) or B (PCYT1B) homodimer condenses phosphocholine (PCho) and cytidine triphosphate (CTP) to produce CDP-choline (CDP-Cho) (Lykidis et al. 1998).

Literature References
PubMed ID Title Journal Year
9593753 Cloning and characterization of a second human CTP:phosphocholine cytidylyltransferase

Lykidis, A, Murti, KG, Jackowski, S

J Biol Chem 1998
Participants
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
choline-phosphate cytidylyltransferase activity of PCYT1 dimer [endoplasmic reticulum membrane]
Physical Entity
Activity
Orthologous Events
Authored
Created