CDP-DAG is converted to PGP by PGS1

Stable Identifier
R-HSA-1482939
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
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At the inner mitochondrial (IM) membrane, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (PGS1) converts cytidine diphosphate-diacylglycerol (CDP-DAG) and glycerol-3-phosphate (G3P) to phosphatidylglycerophosphate (PGP) and cytidine monophosphate (CMP). This event is inferred from rats. The enzyme PGS1 has been characterized in humans (Ota et al. 2004).

Literature References
PubMed ID Title Journal Year
14702039 Complete sequencing and characterization of 21,243 full-length human cDNAs

Ota, T, Suzuki, Y, Nishikawa, T, Otsuki, T, Sugiyama, T, Irie, R, Wakamatsu, A, Hayashi, K, Sato, H, Nagai, K, Kimura, K, Makita, H, Sekine, M, Obayashi, M, Nishi, T, Shibahara, T, Tanaka, T, Ishii, S, Yamamoto, J, Saito, K, Kawai, Y, Isono, Y, Nakamura, Y, Nagahari, K, Murakami, K, Yasuda, T, Iwayanagi, T, Wagatsuma, M, Shiratori, A, Sudo, H, Hosoiri, T, Kaku, Y, Kodaira, H, Kondo, H, Sugawara, M, Takahashi, M, Kanda, K, Yokoi, T, Furuya, T, Kikkawa, E, Omura, Y, Abe, K, Kamihara, K, Katsuta, N, Sato, K, Tanikawa, M, Yamazaki, M, Ninomiya, K, Ishibashi, T, Yamashita, H, Murakawa, K, Fujimori, K, Tanai, H, Kimata, M, Watanabe, M, Hiraoka, S, Chiba, Y, Ishida, S, Ono, Y, Takiguchi, S, Watanabe, S, Yosida, M, Hotuta, T, Kusano, J, Kanehori, K, Takahashi-Fujii, A, Hara, H, Tanase, TO, Nomura, Y, Togiya, S, Komai, F, Hara, R, Takeuchi, K, Arita, M, Imose, N, Musashino, K, Yuuki, H, Oshima, A, Sasaki, N, Aotsuka, S, Yoshikawa, Y, Matsunawa, H, Ichihara, T, Shiohata, N, Sano, S, Moriya, S, Momiyama, H, Satoh, N, Takami, S, Terashima, Y, Suzuki, O, Nakagawa, S, Senoh, A, Mizoguchi, H, Goto, Y, Shimizu, F, Wakebe, H, Hishigaki, H, Watanabe, T, Sugiyama, A, Takemoto, M, Kawakami, B, Yamazaki, M, Watanabe, K, Kumagai, A, Itakura, S, Fukuzumi, Y, Fujimori, Y, Komiyama, M, Tashiro, H, Tanigami, A, Fujiwara, T, Ono, T, Yamada, K, Fujii, Y, Ozaki, K, Hirao, M, Ohmori, Y, Kawabata, A, Hikiji, T, Kobatake, N, Inagaki, H, Ikema, Y, Okamoto, S, Okitani, R, Kawakami, T, Noguchi, S, Itoh, T, Shigeta, K, Senba, T, Matsumura, K, Nakajima, Y, Mizuno, T, Morinaga, M, Sasaki, M, Togashi, T, Oyama, M, Hata, H, Watanabe, M, Komatsu, T, Mizushima-Sugano, J, Satoh, T, Shirai, Y, Takahashi, Y, Nakagawa, K, Okumura, K, Nagase, T, Nomura, N, Kikuchi, H, Masuho, Y, Yamashita, R, Nakai, K, Yada, T, Nakamura, Y, Ohara, O, Isogai, T, Sugano, S

Nat Genet 2004
Participants
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity of PGS1 [mitochondrial inner membrane]
Physical Entity
Activity
Inferred From
Authored
Created