MLCL is acylated to CL by LCLAT1 (ER)

Stable Identifier
R-HSA-1482861
Type
Reaction [transition]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane, cytosol
ReviewStatus
5/5
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MLCL is acylated to CL by LCLAT1 (ER)
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At the endoplasmic reticulum (ER) membrane, lysocardiolipin acyltransferase 1 (LCLAT1) aka ALCAT1 acylates monolysocardiolipin (MLCL) to cardiolipin (CL) (Cao et al. 2004, Zhao et al. 2009).
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Catalyst Activity

O-acyltransferase activity of LCLAT1 [endoplasmic reticulum membrane]

Physical Entity
LCLAT1 [endoplasmic reticulum membrane] (Homo sapiens)
Activity
O-acyltransferase activity (GO:0008374)
Orthologous Events
MLCL is acylated to CL by LCLAT1 (ER) (Bos taurus)
MLCL is acylated to CL by LCLAT1 (ER) (Caenorhabditis elegans)
MLCL is acylated to CL by LCLAT1 (ER) (Canis familiaris)
MLCL is acylated to CL by LCLAT1 (ER) (Danio rerio)
MLCL is acylated to CL by LCLAT1 (ER) (Dictyostelium discoideum)
MLCL is acylated to CL by LCLAT1 (ER) (Gallus gallus)
MLCL is acylated to CL by LCLAT1 (ER) (Mus musculus)
MLCL is acylated to CL by LCLAT1 (ER) (Rattus norvegicus)
MLCL is acylated to CL by LCLAT1 (ER) (Saccharomyces cerevisiae)
MLCL is acylated to CL by LCLAT1 (ER) (Schizosaccharomyces pombe)
MLCL is acylated to CL by LCLAT1 (ER) (Sus scrofa)
MLCL is acylated to CL by LCLAT1 (ER) (Xenopus tropicalis)
Authored
Williams, MG  (2011-09-14)
Created
Williams, MG  (2011-08-12)
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