Reactome | CL transports from the ER to the IM

CL transports from the ER to the IM

Stable Identifier

R-HSA-1482857

Type

Reaction [omitted]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane, mitochondrial inner membrane

ReviewStatus

5/5

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Cardiolipin (CL) transports via membrane contact sites between the endoplasmic reticulum (ER) and the inner mitochondria membranes (IM) (Osman et al. 2011, Vance 1990, Gaigg et al. 1995, Zhao et al. 2009, Simbeni et al. 1991, Ardail et al. 1993, Shiao et al., 1995).

Literature References

PubMed ID	Title	Journal	Year
19075029	The microsomal cardiolipin remodeling enzyme acyl-CoA lysocardiolipin acyltransferase is an acyltransferase of multiple anionic lysophospholipids Zhao, Y, Chen, YQ, Li, S, Konrad, RJ, Cao, G	J Lipid Res	2009
2037561	Mitochondrial membrane contact sites of yeast. Characterization of lipid components and possible involvement in intramitochondrial translocation of phospholipids Simbeni, R, Pon, L, Zinser, E, Paltauf, F, Daum, G	J Biol Chem	1991
7744750	Evidence that phosphatidylserine is imported into mitochondria via a mitochondria-associated membrane and that the majority of mitochondrial phosphatidylethanolamine is derived from decarboxylation of phosphatidylserine Shiao, YJ, Lupo, G, Vance, JE	J Biol Chem	1995
2332429	Phospholipid synthesis in a membrane fraction associated with mitochondria Vance, JE	J Biol Chem	1990
8245031	Involvement of mitochondrial contact sites in the subcellular compartmentalization of phospholipid biosynthetic enzymes Ardail, D, Gasnier, F, Lermé, F, Simonot, C, Louisot, P, Gateau-Roesch, O	J Biol Chem	1993
21220505	Making heads or tails of phospholipids in mitochondria Osman, C, Voelker, DR, Langer, T	J Cell Biol	2011
7696296	Characterization of a microsomal subfraction associated with mitochondria of the yeast, Saccharomyces cerevisiae. Involvement in synthesis and import of phospholipids into mitochondria Gaigg, B, Simbeni, R, Hrastnik, C, Paltauf, F, Daum, G	Biochim Biophys Acta	1995

Participants

Input

CL [endoplasmic reticulum membrane]

Output

cardiolipin [mitochondrial inner membrane]

Participates

as an event of

Acyl chain remodeling of CL (Homo sapiens)

Event Information

Go Biological Process

phospholipid transport (0015914)

Cross References

Rhea

38695

Authored

Williams, MG (2011-09-14)

Created

Williams, MG (2011-08-12)

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