Reactome | MLCL transports from the IM to the ER

MLCL transports from the IM to the ER

Stable Identifier

R-HSA-1482773

Type

Reaction [transition]

Species

Homo sapiens

Compartment

mitochondrial inner membrane, endoplasmic reticulum membrane

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Monolysocardiolipin (MLCL) transports via membrane contact sites between the endoplasmic reticulum (ER) and the inner mitochondria membranes (IM) (Cao et al. 2004, Zhao et al. 2009, Taylor & Hatch 2009).

Literature References

PubMed ID	Title	Journal	Year
15152008	A novel cardiolipin-remodeling pathway revealed by a gene encoding an endoplasmic reticulum-associated acyl-CoA:lysocardiolipin acyltransferase (ALCAT1) in mouse Cao, J, Liu, Y, Lockwood, J, Burn, P, Shi, Y	J Biol Chem	2004
19075029	The microsomal cardiolipin remodeling enzyme acyl-CoA lysocardiolipin acyltransferase is an acyltransferase of multiple anionic lysophospholipids Zhao, Y, Chen, YQ, Li, S, Konrad, RJ, Cao, G	J Lipid Res	2009
19737925	Identification of the human mitochondrial linoleoyl-coenzyme A monolysocardiolipin acyltransferase (MLCL AT-1) Taylor, WA, Hatch, GM	J Biol Chem	2009

Participants

Input

MLCL [mitochondrial inner membrane]

Output

MLCL [endoplasmic reticulum membrane]

Participant Of

hasEvent

Acyl chain remodeling of CL

Authored

Williams, MG (2011-09-14)

Created

Williams, MG (2011-08-12)