Reactome | MLCL transports from the IM to the ER

MLCL transports from the IM to the ER

Stable Identifier

R-HSA-1482773

Type

Reaction

Species

Homo sapiens

Compartment

mitochondrial inner membrane, endoplasmic reticulum membrane

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Monolysocardiolipin (MLCL) transports via membrane contact sites between the endoplasmic reticulum (ER) and the inner mitochondria membranes (IM) (Cao et al. 2004, Zhao et al. 2009, Taylor & Hatch 2009).

Literature References

PubMed ID	Title	Journal	Year
19075029	The microsomal cardiolipin remodeling enzyme acyl-CoA lysocardiolipin acyltransferase is an acyltransferase of multiple anionic lysophospholipids Cao, G, Li, S, Chen, YQ, Zhao, Y, Konrad, RJ	J Lipid Res	2009
15152008	A novel cardiolipin-remodeling pathway revealed by a gene encoding an endoplasmic reticulum-associated acyl-CoA:lysocardiolipin acyltransferase (ALCAT1) in mouse Shi, Y, Lockwood, J, Liu, Y, Burn, P, Cao, J	J Biol Chem	2004
19737925	Identification of the human mitochondrial linoleoyl-coenzyme A monolysocardiolipin acyltransferase (MLCL AT-1) Taylor, WA, Hatch, GM	J Biol Chem	2009