PA is hydrolysed to 1-acyl LPA by PLA2G2A

Stable Identifier
R-HSA-1482679
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

At the endoplasmic reticulum (ER) membrane, phosphatidic acid (PA) is hydrolyzed, and has one of its acyl chains cleaved off, by membrane-associated phospholipase A2 gamma 2A (PLA2G2A), to form 1-acyl lysophosphatidic acid (LPA) (Singer et al. 2002).

Participants
Participant Of
hasEvent
Catalyst Activity
Catalyst Activity
Title
phospholipase A2 activity of PLA2G2A:Ca2+ [endoplasmic reticulum membrane]
Physical Entity
Activity
Orthologous Events
Authored