2-MAG is transacylated to DAG by PNPLA2/3

Stable Identifier
R-HSA-1482654
Type
Reaction [transition]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane, cytosol
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2-MAG is transacylated to DAG by PNPLA2/3
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At the endoplasmic reticulum (ER) membrane, two 2-monoacylglycerol (2-MAG) molecules are transacylated by patatin-like phospholipase domain-containing proteins 2/3 (PNPLA2/3) to form diacylglycerol (DAG) and glycerol (Jenkins et al. 2004).

Literature References
Participants
Input
Output
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Catalyst Activity
Catalyst Activity
Title
acylglycerol O-acyltransferase activity of PNPLA2/3 [endoplasmic reticulum membrane]
Physical Entity
PNPLA2/3 [endoplasmic reticulum membrane]
Activity
acylglycerol O-acyltransferase activity (0016411)
Orthologous Events
2-MAG is transacylated to DAG by PNPLA2/3 (Bos taurus)
2-MAG is transacylated to DAG by PNPLA2/3 (Caenorhabditis elegans)
2-MAG is transacylated to DAG by PNPLA2/3 (Canis familiaris)
2-MAG is transacylated to DAG by PNPLA2/3 (Danio rerio)
2-MAG is transacylated to DAG by PNPLA2/3 (Drosophila melanogaster)
2-MAG is transacylated to DAG by PNPLA2/3 (Gallus gallus)
2-MAG is transacylated to DAG by PNPLA2/3 (Mus musculus)
2-MAG is transacylated to DAG by PNPLA2/3 (Plasmodium falciparum)
2-MAG is transacylated to DAG by PNPLA2/3 (Rattus norvegicus)
2-MAG is transacylated to DAG by PNPLA2/3 (Sus scrofa)
2-MAG is transacylated to DAG by PNPLA2/3 (Xenopus tropicalis)
Authored
Williams, MG  (2011-09-14)
Created
Williams, MG  (2011-08-12)