Reactome | 2-acyl LPI is acylated to PI by MBOAT7

2-acyl LPI is acylated to PI by MBOAT7

Stable Identifier

R-HSA-1482626

Type

Reaction [transition]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane, cytosol

ReviewStatus

5/5

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At the endoplasmic reticulum (ER) membrane, lysophospholipid acyltransferase 7 (MBOAT7) aka LPIAT acylates 2-acyl lysophosphatidylinositol (LPI) to form phosphatidylinositol (PI) (Gijon et al. 2008, Lee et al. 2008).

Literature References

PubMed ID	Title	Journal	Year
18772128	Lysophospholipid acyltransferases and arachidonate recycling in human neutrophils Zarini, S, Voelker, DR, Riekhof, WR, Gijon, MA, Murphy, RC	J Biol Chem	2008
18094042	Caenorhabditis elegans mboa-7, a member of the MBOAT family, is required for selective incorporation of polyunsaturated fatty acids into phosphatidylinositol Kono, N, Matsuda, S, Mitani, S, Arai, H, Gengyo-Ando, K, Inoue, T, Lee, HC, Imae, R, Shirae, S	Mol Biol Cell	2008