2-acyl LPI is acylated to PI by MBOAT7

Stable Identifier
R-HSA-1482626
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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At the endoplasmic reticulum (ER) membrane, lysophospholipid acyltransferase 7 (MBOAT7) aka LPIAT acylates 2-acyl lysophosphatidylinositol (LPI) to form phosphatidylinositol (PI) (Gijon et al. 2008, Lee et al. 2008).

Literature References
PubMed ID Title Journal Year
18094042 Caenorhabditis elegans mboa-7, a member of the MBOAT family, is required for selective incorporation of polyunsaturated fatty acids into phosphatidylinositol

Lee, HC, Inoue, T, Imae, R, Kono, N, Shirae, S, Matsuda, S, Gengyo-Ando, K, Mitani, S, Arai, H

Mol Biol Cell 2008
18772128 Lysophospholipid acyltransferases and arachidonate recycling in human neutrophils

Gijon, MA, Riekhof, WR, Zarini, S, Murphy, RC, Voelker, DR

J Biol Chem 2008
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
2-acylglycerol-3-phosphate O-acyltransferase activity of MBOAT7 [endoplasmic reticulum membrane]
Physical Entity
Activity
Orthologous Events
Authored
Created