Reactome | 2-acyl LPI is acylated to PI by MBOAT7

2-acyl LPI is acylated to PI by MBOAT7

Stable Identifier

R-HSA-1482626

Type

Reaction [transition]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane, cytosol

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At the endoplasmic reticulum (ER) membrane, lysophospholipid acyltransferase 7 (MBOAT7) aka LPIAT acylates 2-acyl lysophosphatidylinositol (LPI) to form phosphatidylinositol (PI) (Gijon et al. 2008, Lee et al. 2008).

Literature References

PubMed ID	Title	Journal	Year
18094042	Caenorhabditis elegans mboa-7, a member of the MBOAT family, is required for selective incorporation of polyunsaturated fatty acids into phosphatidylinositol Lee, HC, Inoue, T, Imae, R, Kono, N, Shirae, S, Matsuda, S, Gengyo-Ando, K, Mitani, S, Arai, H	Mol Biol Cell	2008
18772128	Lysophospholipid acyltransferases and arachidonate recycling in human neutrophils Gijon, MA, Riekhof, WR, Zarini, S, Murphy, RC, Voelker, DR	J Biol Chem	2008