Reactome | 2-acyl LPE is hydrolyzed to GPETA by PLA2G4C

2-acyl LPE is hydrolyzed to GPETA by PLA2G4C

Stable Identifier

R-HSA-1482545

Type

Reaction [transition]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane, cytosol

ReviewStatus

5/5

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2-acyl LPE is hydrolyzed to GPETA by PLA2G4C

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At the endoplasmic reticulum (ER) membrane, membrane-bound cytosolic phospholipase A2 gamma (PLA2G4C) hydrolyzes 2-acyl lysophosphatidylethanolamine (LPE) to produce glycerophosphoethanolamine (GPETA) (Yamashita et al. 2005, Yamashita et al. 2009).

Literature References

PubMed ID	Title	Journal	Year
15944408	Roles of C-terminal processing, and involvement in transacylation reaction of human group IVC phospholipase A2 (cPLA2gamma) Waku, K, Nakanishi, H, Yamashita, A, Kawagishi, N, Kamata, R, Sugiura, T, Suzuki, H	J Biochem	2005
19501189	Subcellular localization and lysophospholipase/transacylation activities of human group IVC phospholipase A2 (cPLA2gamma) Waku, K, Tanaka, K, Kumazawa, T, Yamashita, A, Kamata, R, Sugiura, T, Koga, H, Suzuki, N	Biochim Biophys Acta	2009