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IGHG3 [extracellular region]
Stable Identifier
R-HSA-1478810
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Ig gamma-3 chain C region, IGHG3_HUMAN
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Parasitic Infection Pathways (Homo sapiens)
Leishmania infection (Homo sapiens)
Leishmania parasite growth and survival (Homo sapiens)
Anti-inflammatory response favouring Leishmania parasite infection (Homo sapiens)
FCGR3A-mediated IL10 synthesis (Homo sapiens)
IgG binds LPG1G2 in the amastigote form of Leishmania (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG binds the surface of the amastigote form of Leishmania (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Opsonized leishmania amastigote binds FCGR3 (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma antigens:FCGR3A:CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Phosphorylation and activation of PLCG due to FCGR3A effect (Homo sapiens)
IgG:Leishmania surface:p-FCGR3A:p-6Y-SYK:p-3Y-PLCG [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers:p-6Y-SYK [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Leishmania surface:p-FCGR3As:p-6Y-SYK:PLCG [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers:p-6Y-SYK [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:PLCG [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Recruitment of PLCgamma to membrane due to FCGR3A effect (Homo sapiens)
IgG:Leishmania surface:p-FCGR3As:p-6Y-SYK:PLCG [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers:p-6Y-SYK [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers:p-6Y-SYK [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Release of PLCG from FCGR3A (Homo sapiens)
IgG:Leishmania surface:p-FCGR3A:p-6Y-SYK:p-3Y-PLCG [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers:p-6Y-SYK [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers:p-6Y-SYK [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
SYK binds IgG:Lma antigens:FCGR3A:p-CD3 dimers (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers:SYK [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Src phosphorylate SYK in IgG:Leishmania surface:p-FCGR3A:SYK (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers:SYK [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers:p-6Y-SYK [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Src phosphorylates CD3 dimers in IgG:Lma antigens:FCGR3A:CD3 dimers (Homo sapiens)
IgG:Lma antigens:FCGR3A:CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Parasite infection (Homo sapiens)
Leishmania phagocytosis (Homo sapiens)
FCGR3A-mediated phagocytosis (Homo sapiens)
CRKII:DOCK180:ELMO binds FCGR3A (Homo sapiens)
IgG:Leishmania surface:p-FCGR3A:p-6Y-SYK:CRKII:DOCK180:ELMO [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers:p-6Y-SYK [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers:p-6Y-SYK [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
DOCK180 exchanges GTP for GDP on RAC1:GDP (Homo sapiens)
IgG:Leishmania surface:p-FCGR3A:p-6Y-SYK:CRKII:DOCK180:ELMO [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers:p-6Y-SYK [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG binds LPG1G2 in the amastigote form of Leishmania (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG binds the surface of the amastigote form of Leishmania (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Leishmania surface:FCGR3A translocates from plasma membrane to the parasitophorous vacuole (Homo sapiens)
IgG:Leishmania surface:FCGR3A [phagocytic cup] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma antigens binds FCGR3A:CD3 dimers (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma antigens:FCGR3A:CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
SYK binds IgG:Lma antigens:FCGR3A:p-CD3 dimers (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers:SYK [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Src phosphorylate SYK in IgG:Leishmania surface:p-FCGR3A:SYK (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers:SYK [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers:p-6Y-SYK [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Src phosphorylates CD3 dimers in IgG:Lma antigens:FCGR3A:CD3 dimers (Homo sapiens)
IgG:Lma antigens:FCGR3A:CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
VAV1,2,3:PI(3,4,5)P3 binds p-6Y-SYK (Homo sapiens)
IgG:Leishmania surface:FCGR3Ap-CD3 dimers:p-6Y-SYK:VAV1,2,3:PI(3,4,5)P3 [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers:p-6Y-SYK [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers:p-6Y-SYK [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
p-6Y-SYK phosphorylates VAV1,2,3 (Homo sapiens)
IgG:Leishmania surface:FCGR3Ap-CD3 dimers:p-6Y-SYK:VAV1,2,3:PI(3,4,5)P3 [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers:p-6Y-SYK [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Leishmania surface:p-FCGR3A:p-6Y-SYK:p-VAV1,2,3:PI(3,4,5)P3 [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers:p-6Y-SYK [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers:p-6Y-SYK [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
p-VAV1,2,3 exchanges GTP for GDP on RAC1:GDP (Homo sapiens)
IgG:Leishmania surface:p-FCGR3A:p-6Y-SYK:p-VAV1,2,3:PI(3,4,5)P3 [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers:p-6Y-SYK [plasma membrane] (Homo sapiens)
IgG:Lma antigens:FCGR3A:p-CD3 dimers [plasma membrane] (Homo sapiens)
IgG:Lma antigens [plasma membrane] (Homo sapiens)
IgG:LPG1G2 [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG:Lma amastigote surface [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Complement cascade (Homo sapiens)
Initial triggering of complement (Homo sapiens)
Conversion of C2 into C2a and C2b (Homo sapiens)
C4 activators [plasma membrane] (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Conversion of C4 into C4a and C4b (Homo sapiens)
C4 activators [plasma membrane] (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Creation of C4 and C2 activators (Homo sapiens)
Classical antibody-mediated complement activation (Homo sapiens)
Activation of C1r (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2xC1S [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Antigen:IgG:C1Q:2xC1R:2xC1S [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Activation of C1s (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2xC1S [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Regulation of Complement cascade (Homo sapiens)
Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 dissociates (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 [extracellular region] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
C1-Inh binds Antigen: antibody: C1 complex activated C1r, C1s (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Antigen:IgG:C1Q:2xActivated C1R:2xActivated C1S [plasma membrane] (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
C1-Inh binds and inactivates C1r, C1s (Homo sapiens)
Antigen:IgG:C1Q:2xActivated C1R:2xActivated C1S [plasma membrane] (Homo sapiens)
Antigen:IgG:C1Q:2x Activated C1R:2x Activated C1S [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Antigen:IgG:C1Q:2xActivated C1R:SERPING1:2xActivated C1S:SERPING1 [extracellular region] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Fcgamma receptor (FCGR) dependent phagocytosis (Homo sapiens)
FCGR activation (Homo sapiens)
Cross-linking of FCGRIA with IgG-coated Ag (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG-Ag:FCGRIA:CD3G homodimer [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Cross-linking of FCGRIIA with IgG-coated Ag (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG-Ag:FCGRIIA [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Cross-linking of FCGRIIIA with IgG-coated Ag (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
IgG-Ag:FCGRIIIA:CD3G/CD3Z dimers [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Phosphorylation of SYK by Src kinases (Homo sapiens)
clustered IgG-Ag:p-FCGRs:SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Recruitment of SYK to phosphorylated ITAMs (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Sequestering and phosphorylation Fc gamma receptors in the lipid rafts (Homo sapiens)
clustered IgG-Ag:FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Regulation of actin dynamics for phagocytic cup formation (Homo sapiens)
Activation of RAC1 by CRKII:DOCK180:ELMO (Homo sapiens)
CRKII:DOCK180:ELMO complex recruited to phagocytic cup [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Activation of RAC1 by VAV (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-VAV [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Phosphorylation of VAV (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:VAV [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-VAV [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Recruitment of CRKII:DOCK180:ELMO complex to FCGR (Homo sapiens)
CRKII:DOCK180:ELMO complex recruited to phagocytic cup [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Recruitment of VAV1 to p-6Y-SYK (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:VAV [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Role of myosins in phagosome formation (Homo sapiens)
clustered IgG-Ag:p-FCGRs [phagocytic cup] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Role of phospholipids in phagocytosis (Homo sapiens)
PI3K binds to p-6Y-SYK (Homo sapiens)
PI3K:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
PI3K:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Phosphorylation and activation of PLCG (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:PLCG [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-3Y-PLCG [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Recruitment of PLCgamma to membrane (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:PLCG [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
Release of PLCG from FCGR (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK:p-3Y-PLCG [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs:p-6Y-SYK [plasma membrane] (Homo sapiens)
clustered IgG-Ag:p-FCGRs [plasma membrane] (Homo sapiens)
Antigen:IgG [plasma membrane] (Homo sapiens)
IgG [extracellular region] (Homo sapiens)
IgG Heavy Chain [extracellular region] (Homo sapiens)
IgG C region [extracellular region] (Homo sapiens)
IGHG3 [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P01860 IGHG3
Gene Names
IGHG3
Chain
chain:1-446
Reference Genes
HGNC:5527 IGHG3
OMIM:147120 IGHG3
UCSC:P01860 IGHG3
Participates
as a member of
IgG C region [extracellular region] (Homo sapiens)
Inferred To
IGHG3 [extracellular region]
(Bos taurus)
IGHG3 [extracellular region]
(Canis familiaris)
IGHG3 [extracellular region]
(Rattus norvegicus)
IGHG3 [extracellular region]
(Sus scrofa)
Ighg1 [extracellular region]
(Mus musculus)
Cross References
OpenTargets
ENSG00000211897
GeneCards
P01860
PRO
P01860
Pharos - Targets
P01860
PDB
5W38
,
4ZNC
,
6G1E
,
6D58
,
5M3V
,
4WWI
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P30838 ALDH3A1
1
ALDH3A1 [cytosol]
(R-HSA-5692291)
0.527
2
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