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GCHFR [cytosol]
Stable Identifier
R-HSA-1474159
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
GTP cyclohydrolase 1 feedback regulatory protein, GFRP_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of cofactors (Homo sapiens)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Homo sapiens)
GCH1 reduces GTP to dihydroneopterin triphosphate (Homo sapiens)
2GCHFR:GCH1 [cytosol] (Homo sapiens)
GCHFR pentamer [cytosol] (Homo sapiens)
GCHFR [cytosol] (Homo sapiens)
GCHFR binds to GCH1 and negatively regulates its activity (Homo sapiens)
2GCHFR:GCH1 [cytosol] (Homo sapiens)
GCHFR pentamer [cytosol] (Homo sapiens)
GCHFR [cytosol] (Homo sapiens)
GCHFR pentamer [cytosol] (Homo sapiens)
GCHFR [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P30047 GCHFR
Gene Names
GCHFR, GFRP
Chain
initiator methionine:, chain:2-84
Reference Genes
BioGPS Gene:2644 GCHFR
COSMIC (genes):GCHFR GCHFR
CTD Gene:2644 GCHFR
dbSNP Gene:2644 GCHFR
ENSEMBL:ENSG00000137880 GCHFR
HGNC:4194 GCHFR
KEGG:hsa:2644 GCHFR
Monarch:2644 GCHFR
NCBI Gene:2644 GCHFR
OMIM:602437 GCHFR
UCSC:P30047 GCHFR
Reference Transcript
RefSeq:NM_005258.2 GCHFR
Other Identifiers
11723063_a_at
16799653
204867_PM_at
204867_at
2644
3590110
3590111
3590112
3590113
3590114
3590115
3590116
3590117
3590118
40684_at
7982805
A_23_P77328
GE58359
GO:0003824
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0009890
GO:0016020
GO:0016787
GO:0030425
GO:0031410
GO:0031965
GO:0042470
GO:0043226
GO:0044549
GO:0045428
HMNXSV003007111
ILMN_1694780
PH_hs_0023208
TC15000293.hg
U78190_rna1_at
g6382072_3p_at
g6382072_3p_x_at
Participates
as a component of
GCHFR pentamer [cytosol] (Homo sapiens)
Inferred To
GCHFR [cytosol]
(Bos taurus)
GCHFR [cytosol]
(Canis familiaris)
GCHFR [cytosol]
(Gallus gallus)
gchfr [cytosol]
(Xenopus tropicalis)
Gchfr [cytosol]
(Mus musculus)
Gchfr [cytosol]
(Rattus norvegicus)
gfrp-1 [cytosol]
(Caenorhabditis elegans)
Cross References
ENSEMBL
ENST00000559445
,
ENSP00000260447
,
ENSG00000137880
,
ENST00000260447
,
ENSP00000453871
OpenTargets
ENSG00000137880
GeneCards
GCHFR
HPA
ENSG00000137880-GCHFR
PRO
P30047
Pharos - Targets
P30047
HMDB Protein
HMDBP01961
PDB
6Z80
,
7ALQ
,
7ALA
,
7ALC
,
7ALB
,
7AL9
,
6Z85
,
7ACC
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