Reactome | CLEC4M [plasma membrane]

CLEC4M [plasma membrane]

Stable Identifier

R-HSA-1472862

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

C-type lectin domain family 4 member M, CLC4M_HUMAN

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - Respiratory Syncytial Virus Infection Pathway (Homo sapiens)
      - RSV-host interactions (Homo sapiens)
        
        RSV G binds CD209,CLEC4M (Homo sapiens)
        
        CD209,CLEC4M [plasma membrane] (Homo sapiens)
        
        CLEC4M [plasma membrane] (Homo sapiens)
        
        RSV virion:CD209,CLEC4M [plasma membrane] (Homo sapiens)
        
        CD209,CLEC4M [plasma membrane] (Homo sapiens)
        
        CLEC4M [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9H2X3 CLEC4M

Gene Names

CLEC4M, CD209L, CD209L1, CD299

Chain

chain:1-399

Reference Genes

BioGPS Gene:10332 CLEC4M

COSMIC (genes):CLEC4M CLEC4M

CTD Gene:10332 CLEC4M

dbSNP Gene:10332 CLEC4M

ENSEMBL:ENSG00000104938 CLEC4M

HGNC:13523 CLEC4M

KEGG:hsa:10332 CLEC4M

Monarch:10332 CLEC4M

NCBI Gene:10332 CLEC4M

OMIM:605872 CLEC4M

UCSC:Q9H2X3 CLEC4M

Reference Transcript

Other Identifiers

10332

11733341_a_at

11740839_a_at

11742268_x_at

11742269_x_at

11745081_a_at

11745082_x_at

11749203_x_at

11750462_a_at

11750463_a_at

11750464_x_at

16857748

207995_PM_s_at

207995_s_at

210481_PM_s_at

210481_s_at

3819131

3819132

3819133

3819134

3819135

3819136

3819137

3819138

3819139

3819140

3819141

3819142

3819143

3819144

3819145

3819146

3819147

3819148

3819149

3819150

3819151

3819152

3819153

3848547

3848549

3848552

3848553

39270_at

8025303

A_14_P123883

A_23_P208482

A_24_P246196

A_24_P53465

GE53413

GO:0001618

GO:0002250

GO:0002376

GO:0005515

GO:0005537

GO:0005576

GO:0005737

GO:0005886

GO:0006897

GO:0006955

GO:0007155

GO:0007159

GO:0009897

GO:0009988

GO:0016020

GO:0016192

GO:0019062

GO:0019065

GO:0019079

GO:0019882

GO:0030246

GO:0030369

GO:0035556

GO:0038023

GO:0042605

GO:0043657

GO:0045087

GO:0046718

GO:0046790

GO:0046813

GO:0046872

GO:0046968

GO:0048306

GO:0060089

GO:0075733

GO:0098542

HMNXSV003020253

HMNXSV003033922

ILMN_2322131

PH_hs_0033267

TC19000136.hg

TC19001958.hg

g12084796_3p_a_at

g7657173_3p_x_at

Participates

as a member of

CD209,CLEC4M [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001138380.1, NP_001138381.1, NP_001138378.1, NP_001138377.1, NP_001138382.1, XP_006722678.1, NP_001138383.1, NP_001138379.1, NP_055072.3

OpenTargets

ENSG00000104938

ENSEMBL

ENSP00000316228, ENSP00000471125, ENST00000596363, ENST00000327325

HPA

ENSG00000104938-CLEC4M

PRO

Q9H2X3

Pharos - Targets

Q9H2X3

GlyGen

Q9H2X3

PDB

1XPH, 3JQH, 1K9J, 1SL6, 1XAR

HMDB Protein

HMDBP02923

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTC2 S	20	S(686-815) [plasma membrane] (R-COV-9770188) Spike S2' Fragment [plasma membrane] (R-COV-9770189) S1 [plasma membrane] (R-COV-9769950) fully glycosylated Spike [plasma membrane] (R-COV-9733472) nascent Spike [endoplasmic reticulum lumen] (R-COV-9694796) 14-sugar N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9694459) Man(9) N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9696892) high-mannose N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9696875) high-mannose N-glycan folded Spike [endoplasmic reticulum lumen] (R-COV-9696880) high-mannose N-glycan folded Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9766369) high-mannose N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696943) di-antennary N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696920) complex N-glycan-PALM-Spike S1 Fragment [virion membrane] (R-COV-9694638) complex N-glycan-PALM-Spike S2 Fragment [virion membrane] (R-COV-9694791) complex N-glycan-PALM-Spike S2 Fragment [endocytic vesicle membrane] (R-COV-9694343) complex N-glycan-PALM-Spike S1 Fragment [endocytic vesicle membrane] (R-COV-9694745) fully glycosylated Spike [virion membrane] (R-COV-9698327) fully glycosylated Spike [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9698330) complex N-glycan-PALM-Spike S2 Fragment [plasma membrane] (R-COV-9769952) fully glycosylated Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696997)	0.857	12
UniProt:Q9BYF1 ACE2	5	glycosylated-ACE2 [plasma membrane] (R-HSA-9683480) ACE2 [endocytic vesicle membrane] (R-HSA-9698958) glycosylated-ACE2 [endocytic vesicle membrane] (R-HSA-9686721) ACE2 [endoplasmic reticulum lumen] (R-HSA-9683474) ACE2(18-805) [plasma membrane] (R-HSA-2022344)	0.591	3
UniProt:Q8IY26 PLPP6	1	PLPP6 [plasma membrane] (R-HSA-8952144)	0.556	3

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