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DEFB1(?-68) [Golgi lumen]
Stable Identifier
R-HSA-1467268
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi lumen
Synonyms
Beta-defensin 1, DEFB1_HUMAN, DEFB1
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Antimicrobial peptides (Homo sapiens)
Defensins (Homo sapiens)
Beta defensins (Homo sapiens)
Beta-defensins are secreted (Homo sapiens)
Beta-defensins [Golgi lumen] (Homo sapiens)
DEFB1(?-68) [Golgi lumen] (Homo sapiens)
Pre-pro-defensins are cleaved to remove the signal peptide (Homo sapiens)
Pro-defensins [Golgi lumen] (Homo sapiens)
DEFB1(?-68) [Golgi lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P60022 DEFB1
Gene Names
DEFB1, BD1, HBD1
Chain
signal peptide:1-21, propeptide:22-32, peptide:33-68
Reference Genes
BioGPS Gene:1672 DEFB1
COSMIC (genes):DEFB1 DEFB1
CTD Gene:1672 DEFB1
dbSNP Gene:1672 DEFB1
ENSEMBL:ENSG00000164825 DEFB1
HGNC:2766 DEFB1
KEGG:hsa:1672 DEFB1
Monarch:1672 DEFB1
NCBI Gene:1672 DEFB1
OMIM:602056 DEFB1
UCSC:P60022 DEFB1
Reference Transcript
RefSeq:NM_005218.3 DEFB1
Other Identifiers
11723845_a_at
11723846_at
1672
17074296
210397_PM_at
210397_at
3122686
3122687
3122688
3122692
3122693
39660_at
8149097
GE60155
GO:0002227
GO:0002376
GO:0005515
GO:0005576
GO:0005615
GO:0005796
GO:0006935
GO:0006952
GO:0006955
GO:0007186
GO:0009617
GO:0016020
GO:0019722
GO:0019731
GO:0022414
GO:0031731
GO:0042742
GO:0042802
GO:0043226
GO:0045087
GO:0050829
GO:0050830
GO:0060474
GO:0061844
GO:0070062
GO:0097225
GO:0098542
GO:1990742
HMNXSV003019613
ILMN_1686573
TC08000906.hg
X92744_at
g1755147_3p_at
Participates
as a member of
Pro-defensins [Golgi lumen] (Homo sapiens)
Beta-defensins [Golgi lumen] (Homo sapiens)
Other forms of this molecule
DEFB1(1-68) [Golgi lumen]
DEFB1(?-68) [extracellular region]
Inferred To
AvBD14 [Golgi lumen]
(Gallus gallus)
DEFB1(?-68) [Golgi lumen]
(Bos taurus)
CBD1 [Golgi lumen]
(Canis familiaris)
DEFB1 [Golgi lumen]
(Sus scrofa)
Defb1 [Golgi lumen]
(Mus musculus)
Defb1 [Golgi lumen]
(Rattus norvegicus)
Cross References
ENSEMBL
ENSG00000164825
,
ENST00000642865
,
ENSP00000494448
,
ENSG00000284881
,
ENST00000297439
,
ENSP00000297439
OpenTargets
ENSG00000164825
GeneCards
DEFB1
HPA
ENSG00000164825-DEFB1
PRO
P60022
Pharos - Targets
P60022
PDB
1KJ5
,
2NLP
,
1IJV
,
2NLQ
,
1IJU
,
2NLS
,
2NLH
,
1E4S
,
2NLD
,
2NLF
,
2NLG
,
2NLE
,
2NLC
,
2NLB
,
2PLZ
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O60551 NMT2
1
NMT2 [cytosol]
(R-HSA-184377)
0.527
2
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