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Sialyl-2,3 T-antigen (MUC5B) [Golgi lumen]
Stable Identifier
R-HSA-1463597
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi lumen
Synonyms
MUC5B, MUC5B_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
O-linked glycosylation (Homo sapiens)
O-linked glycosylation of mucins (Homo sapiens)
Termination of O-glycan biosynthesis (Homo sapiens)
ST3GAL1-4 transfers sialic acid to the T antigen at the alpha 3 position (Homo sapiens)
Sialyl-2,3 T antigens [Golgi lumen] (Homo sapiens)
Sialyl-2,3 T-antigen (MUC5B) [Golgi lumen] (Homo sapiens)
ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen (Homo sapiens)
Sialyl-2,3 T antigens [Golgi lumen] (Homo sapiens)
Sialyl-2,3 T-antigen (MUC5B) [Golgi lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9HC84 MUC5B
Gene Names
MUC5B, MUC5
Chain
signal peptide:1-25, chain:26-5762
Reference Genes
BioGPS Gene:727897 MUC5B
COSMIC (genes):MUC5B MUC5B
CTD Gene:727897 MUC5B
dbSNP Gene:727897 MUC5B
ENSEMBL:ENSG00000117983 MUC5B
HGNC:7516 MUC5B
KEGG:hsa:727897 MUC5B
Monarch:727897 MUC5B
NCBI Gene:727897 MUC5B
OMIM:600770 MUC5B
UCSC:Q9HC84 MUC5B
Reference Transcript
RefSeq:NM_002458.2 MUC5B
Other Identifiers
11744063_a_at
11744064_at
11748931_a_at
16720601
213432_PM_at
213432_at
222268_3p_x_at
222268_PM_x_at
222268_x_at
3316713
3316714
3316715
3316717
3316718
3316719
3316720
3316721
3316722
3316723
3316724
3316725
3316726
3316727
3316728
3316729
3316730
3316731
3316733
3316734
3316735
3316736
3316737
3316738
3316741
3316742
3316743
3316744
3316745
3316746
3316747
3316748
3316749
3316750
3316751
3316752
3316753
3316754
3316755
3316756
3316757
3316758
3316759
3316760
3316761
3316762
3316763
3316764
3316765
3316766
3316767
3316768
3316769
3316770
3316771
3316772
3316773
3316774
3316775
3316776
3316777
3316778
3316779
3316780
3316781
3316783
3316784
3316785
3316786
3316787
3316788
3316789
3316790
3316791
3316792
3316793
3316794
3316795
3316796
3316797
3316798
3316799
3316800
3316801
3316802
3316804
3316805
3316806
3316807
3316808
41365_at
60740_at
694_at
727897
7937612
A_23_P305863
A_24_P102650
A_24_P324141
A_24_P916789
GE564339
GE60272
GO:0005515
GO:0005576
GO:0005615
GO:0005796
GO:0005886
GO:0030312
GO:0031012
GO:0043226
GO:0043231
GO:0046872
GO:0070062
HMNXSV003052173
Hs.102482.1.A1_3p_at
Hs.321110.0.S1_3p_at
Hs.321110.0.S1_3p_x_at
ILMN_1693983
PH_hs_0040975
TC11002495.hg
TC11002497.hg
TC11002498.hg
TC11002499.hg
TC11003510.hg
U78551_at
Participates
as a member of
Sialyl-2,3 T antigens [Golgi lumen] (Homo sapiens)
Other forms of this molecule
GalNAc-MUC5B(26-5703) [plasma membrane]
Core 2 (MUC5B) [Golgi lumen]
Core 2a (MUC5B) [Golgi lumen]
GalNAc-MUC5B(26-5703) [Golgi lumen]
Sialyl Tn antigen (MUC5B) [Golgi lumen]
T-antigen (MUC5B) [Golgi lumen]
Sialyl T-antigen (MUC5B) [Golgi lumen]
Disialyl T-antigen (MUC5B) [Golgi lumen]
MUC5B(26-5703) [Golgi lumen]
Core 6 (MUC5B) [Golgi lumen]
extended Core 6 (MUC5B) [Golgi lumen]
Core 7 (MUC5B) [Golgi lumen]
Core 3 (MUC5B) [Golgi lumen]
Core 4 (MUC5B) [Golgi lumen]
Core 5 (MUC5B) [Golgi lumen]
Core 2S (MUC5B) [Golgi lumen]
Core 8 (MUC5B) [Golgi lumen]
Inferred To
Muc5b [Golgi lumen]
(Mus musculus)
Muc5b [Golgi lumen]
(Rattus norvegicus)
MUC5B [Golgi lumen]
(Sus scrofa)
Hml [Golgi lumen]
(Drosophila melanogaster)
Sialyl-2,3 T-antigen (MUC5B) [Golgi lumen]
(Bos taurus)
Sialyl-2,3 T-antigen (MUC5B) [Golgi lumen]
(Gallus gallus)
Modified Residues
Name
O-(N-acetylamino)galactosyl-L-serine (alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl group) at unknown position
Modification
alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl group
PsiMod Name
O-(N-acetylamino)galactosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-(N-acetylaminogalactosyl)-L-serine.
Cross References
RefSeq
NP_002449.2
OpenTargets
ENSG00000117983
ENSEMBL
ENSP00000436812
,
ENST00000529681
HPA
ENSG00000117983-MUC5B
PRO
Q9HC84
Pharos - Targets
Q9HC84
GlyGen
Q9HC84
Orphanet
MUC5B
PDB
8OES
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q16822 PCK2
1
PCK2 [mitochondrial matrix]
(R-HSA-372815)
0.527
2
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