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Sialyl Tn antigen (MUC7) [Golgi lumen]
Stable Identifier
R-HSA-1463593
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi lumen
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
O-linked glycosylation (Homo sapiens)
O-linked glycosylation of mucins (Homo sapiens)
Termination of O-glycan biosynthesis (Homo sapiens)
ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens (Homo sapiens)
Sialyl Tn antigens [Golgi lumen] (Homo sapiens)
Sialyl Tn antigen (MUC7) [Golgi lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8TAX7 MUC7
Gene Names
MUC7, MG2
Chain
signal peptide:1-22, chain:23-377
Reference Genes
BioGPS Gene:4589 MUC7
COSMIC (genes):MUC7 MUC7
CTD Gene:4589 MUC7
dbSNP Gene:4589 MUC7
ENSEMBL:ENSG00000171195 MUC7
HGNC:7518 MUC7
KEGG:hsa:4589 MUC7
Monarch:4589 MUC7
NCBI Gene:4589 MUC7
OMIM:158375 MUC7
UCSC:Q8TAX7 MUC7
Reference Transcript
RefSeq:NM_152291.2 MUC7
RefSeq:NM_001145006.1 MUC7
RefSeq:NM_001145007.1 MUC7
Other Identifiers
11736279_a_at
16967505
217059_PM_at
217059_at
2730436
2730437
2730438
2730440
2730441
2730442
2730443
2730444
2730445
2730446
2730447
2730448
31706_at
4589
8095504
A_14_P125933
A_14_P201876
A_23_P121614
GE533121
GO:0002376
GO:0005515
GO:0005576
GO:0005796
GO:0005886
GO:0031640
GO:0043226
GO:0061844
GO:0070062
GO:0098542
HMNXSV003031811
Hs.103944.0.S1_3p_at
ILMN_1798931
PH_hs_0005767
TC04000386.hg
Participates
as a member of
Sialyl Tn antigens [Golgi lumen] (Homo sapiens)
Other forms of this molecule
GalNAc-MUC7 [plasma membrane]
Core 2 (MUC7) [Golgi lumen]
Core 2a (MUC7) [Golgi lumen]
GalNAc-MUC7 [Golgi lumen]
T-antigen (MUC7) [Golgi lumen]
Sialyl-2,3 T-antigen (MUC7) [Golgi lumen]
Sialyl T-antigen (MUC7) [Golgi lumen]
Disialyl T-antigen (MUC7) [Golgi lumen]
MUC7 [Golgi lumen]
Core 6 (MUC7) [Golgi lumen]
extended Core 6 (MUC7) [Golgi lumen]
Core 7 (MUC7) [Golgi lumen]
Core 3 (MUC7) [Golgi lumen]
Core 4 (MUC7) [Golgi lumen]
Core 5 (MUC7) [Golgi lumen]
Core 2S (MUC7) [Golgi lumen]
Core 8 (MUC7) [Golgi lumen]
Modified Residues
Name
O-(N-acetylamino)galactosyl-L-serine (Neu5Ac-alpha2,6-GalNAc-alpha group) at unknown position
Modification
Neu5Ac-alpha2,6-GalNAc-alpha group
PsiMod Name
O-(N-acetylamino)galactosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-(N-acetylaminogalactosyl)-L-serine.
Cross References
RefSeq
NP_689504.2
,
NP_001138478.1
,
NP_001138479.1
ENSEMBL
ENSP00000302021
,
ENST00000304887
,
ENST00000413702
,
ENSP00000400585
,
ENST00000456088
,
ENSP00000407422
OpenTargets
ENSG00000171195
HPA
ENSG00000171195-MUC7
PRO
Q8TAX7
Pharos - Targets
Q8TAX7
GlyGen
Q8TAX7
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q00403 GTF2B
1
GTF2B [nucleoplasm]
(R-HSA-65888)
0.527
2
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