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Disialyl T-antigen (MUC5AC) [Golgi lumen]
Stable Identifier
R-HSA-1463497
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi lumen
Synonyms
MUC5AC, MUC5A_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
O-linked glycosylation (Homo sapiens)
O-linked glycosylation of mucins (Homo sapiens)
Termination of O-glycan biosynthesis (Homo sapiens)
ST6GALNAC3/4 transfers sialic acid to the sialyl T antigen to form the disialyl T antigen (Homo sapiens)
Disialyl T antigens [Golgi lumen] (Homo sapiens)
Disialyl T-antigen (MUC5AC) [Golgi lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P98088 MUC5AC
Gene Names
MUC5AC, MUC5
Chain
signal peptide:1-27, chain:28-5654
Reference Genes
BioGPS Gene:4586 MUC5AC
COSMIC (genes):MUC5AC MUC5AC
CTD Gene:4586 MUC5AC
dbSNP Gene:4586 MUC5AC
ENSEMBL:ENSG00000215182 MUC5AC
ENSEMBL_homo_sapiens_GENE:ENSG00000215182.8 MUC5AC
ENSEMBL_homo_sapiens_GENE:ENSG00000291363.1 MUC5AC
HGNC:7515 MUC5AC
KEGG Gene (Homo sapiens):4586 MUC5AC
Monarch:4586 MUC5AC
NCBI Gene:4586 MUC5AC
OMIM:158373 MUC5AC
UCSC:P98088 MUC5AC
Reference Transcript
RefSeq:NM_001304359.1 MUC5AC
Other Identifiers
16720560
214303_PM_x_at
214303_x_at
214385_PM_s_at
214385_s_at
217187_PM_at
217187_at
298_at
41383_at
4586
A_24_P548274
A_24_P743708
A_24_P917886
A_24_P935054
A_33_P3216568
A_33_P3216570
GE60413
GE727017
GO:0005198
GO:0005201
GO:0005515
GO:0005576
GO:0005615
GO:0005794
GO:0005796
GO:0005886
GO:0030312
GO:0031012
GO:0043226
GO:0046872
GO:0070062
GO:0070701
HMNXSV003005895
HMNXSV003019591
Hs.102482.0.A1_3p_s_at
Hs.103707.0.S1_3p_s_at
Hs.247953.0.S1_3p_at
Hs.247953.0.S1_3p_x_at
ILMN_1748303
PH_hs_0031488
PH_hs_0036201
TC11000041.hg
TC11002496.hg
TC11003511.hg
Z48314_s_at
Participates
as a member of
Disialyl T antigens [Golgi lumen] (Homo sapiens)
Other forms of this molecule
Core 8 (MUC5AC) [Golgi lumen]
Core 2S (MUC5AC) [Golgi lumen]
Core 5 (MUC5AC) [Golgi lumen]
Core 4 (MUC5AC) [Golgi lumen]
Core 3 (MUC5AC) [Golgi lumen]
Core 7 (MUC5AC) [Golgi lumen]
extended Core 6 (MUC5AC) [Golgi lumen]
Core 6 (MUC5AC) [Golgi lumen]
GalNAc-MUC5AC [plasma membrane]
Core 2 (MUC5AC) [Golgi lumen]
Core 2a (MUC5AC) [Golgi lumen]
GalNAc-MUC5AC [Golgi lumen]
Sialyl Tn antigen (MUC5AC) [Golgi lumen]
T-antigen (MUC5AC) [Golgi lumen]
Sialyl-2,3 T-antigen (MUC5AC) [Golgi lumen]
Sialyl T-antigen (MUC5AC) [Golgi lumen]
MUC5AC [Golgi lumen]
Inferred To
MUC5AC [Golgi lumen]
(Sus scrofa)
Muc5ac [Golgi lumen]
(Mus musculus)
Muc5ac [Golgi lumen]
(Rattus norvegicus)
Hml [Golgi lumen]
(Drosophila melanogaster)
Disialyl T-antigen (MUC5AC) [Golgi lumen]
(Bos taurus)
Modified Residues
Name
O-(N-acetylamino)galactosyl-L-serine (Neu5Ac-2,6(Neu5Ac-alpha2,3Gal-beta1,3)GalNAc-alpha group) at unknown position
Modification
Neu5Ac-2,6(Neu5Ac-alpha2,3Gal-beta1,3)GalNAc-alpha group
PsiMod Name
O-(N-acetylamino)galactosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-(N-acetylaminogalactosyl)-L-serine.
Cross References
RefSeq
NP_001291288.1
OpenTargets
ENSG00000215182
GeneCards
P98088
HPA
ENSG00000215182-MUC5AC
Ensembl
ENSG00000215182
,
ENSP00000485659
,
ENST00000621226
PRO
P98088
Pharos - Targets
P98088
PDB
5AJN
,
8OV0
,
5AJO
,
5AJP
,
8V9Q
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