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GalNAc-MUC19(?-6254) [Golgi lumen]
Stable Identifier
R-HSA-1463448
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi lumen
Synonyms
Tn antigen (MUC19)
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Diseases of glycosylation (Homo sapiens)
Diseases associated with O-glycosylation of proteins (Homo sapiens)
Defective C1GALT1C1 causes TNPS (Homo sapiens)
Defective C1GALT1C1 does not bind C1GALT1 (Homo sapiens)
Tn antigens [Golgi lumen] (Homo sapiens)
GalNAc-MUC19(?-6254) [Golgi lumen] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
O-linked glycosylation (Homo sapiens)
O-linked glycosylation of mucins (Homo sapiens)
Addition of GalNAc to the Tn antigen via an alpha-1,6 linkage forms a Core 7 glycoprotein (Homo sapiens)
Tn antigens [Golgi lumen] (Homo sapiens)
GalNAc-MUC19(?-6254) [Golgi lumen] (Homo sapiens)
Addition of GlcNAc to the Tn antigen forms a Core 3 glycoprotein (Homo sapiens)
Tn antigens [Golgi lumen] (Homo sapiens)
GalNAc-MUC19(?-6254) [Golgi lumen] (Homo sapiens)
Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Homo sapiens)
Tn antigens [Golgi lumen] (Homo sapiens)
GalNAc-MUC19(?-6254) [Golgi lumen] (Homo sapiens)
Addition of GlcNAc to the Tn antigen via an alpha-1,3 linkage forms a Core 5 glycoprotein (Homo sapiens)
Tn antigens [Golgi lumen] (Homo sapiens)
GalNAc-MUC19(?-6254) [Golgi lumen] (Homo sapiens)
Addition of galactose to the Tn antigen via an alpha-1,3 linkage forms a Core 8 glycoprotein (Homo sapiens)
Tn antigens [Golgi lumen] (Homo sapiens)
GalNAc-MUC19(?-6254) [Golgi lumen] (Homo sapiens)
C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) (Homo sapiens)
Tn antigens [Golgi lumen] (Homo sapiens)
GalNAc-MUC19(?-6254) [Golgi lumen] (Homo sapiens)
GALNTs transfer GalNAc to Mucins to form Tn antigens (Homo sapiens)
Tn antigens [Golgi lumen] (Homo sapiens)
GalNAc-MUC19(?-6254) [Golgi lumen] (Homo sapiens)
Termination of O-glycan biosynthesis (Homo sapiens)
ST6GAL1 transfers sialic acid to Tn antigens to form sTn antigens (Homo sapiens)
Tn antigens [Golgi lumen] (Homo sapiens)
GalNAc-MUC19(?-6254) [Golgi lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q7Z5P9 MUC19
Gene Names
MUC19
Chain
signal peptide:1-21, chain:22-8384
Reference Genes
BioGPS Gene:283463 MUC19
COSMIC (genes):MUC19 MUC19
CTD Gene:283463 MUC19
dbSNP Gene:283463 MUC19
HGNC:14362 MUC19
KEGG Gene (Homo sapiens):283463 MUC19
Monarch:283463 MUC19
NCBI Gene:283463 MUC19
OMIM:612170 MUC19
Reference Transcript
RefSeq:NM_173600.2 MUC19
Participates
as a member of
Tn antigens [Golgi lumen] (Homo sapiens)
Other forms of this molecule
Core 8 (MUC19) [Golgi lumen]
Core 2S (MUC19) [Golgi lumen]
GalNAc-MUC19(?-6254) [plasma membrane]
Core 2 (MUC19) [Golgi lumen]
Core 2a (MUC19) [Golgi lumen]
Sialyl Tn antigen (MUC19) [Golgi lumen]
T-antigen (MUC19) [Golgi lumen]
Sialyl-2,3 T-antigen (MUC19) [Golgi lumen]
Sialyl T-antigen (MUC19) [Golgi lumen]
Disialyl T-antigen (MUC19) [Golgi lumen]
MUC19(?-6254) [Golgi lumen]
Core 6 (MUC19) [Golgi lumen]
extended Core 6 (MUC19) [Golgi lumen]
Core 7 (MUC19) [Golgi lumen]
Core 3 (MUC19) [Golgi lumen]
Core 4 (MUC19) [Golgi lumen]
Core 5 (MUC19) [Golgi lumen]
Inferred To
GalNAc-MUC19(?-6254) [Golgi lumen]
(Dictyostelium discoideum)
GalNAc-MUC19(?-6254) [Golgi lumen]
(Plasmodium falciparum)
Muc19 [Golgi lumen]
(Mus musculus)
Muc19 [Golgi lumen]
(Rattus norvegicus)
Modified Residues
Name
O-(N-acetylamino)galactosyl-L-serine at unknown position
PsiMod Name
O-(N-acetylamino)galactosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-(N-acetylaminogalactosyl)-L-serine.
Cross References
RefSeq
NP_775871.2
OpenTargets
ENSG00000205592
GeneCards
Q7Z5P9
PRO
Q7Z5P9
Pharos - Targets
Q7Z5P9
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