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T-antigen (MUC6) [Golgi lumen]
Stable Identifier
R-HSA-1462322
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi lumen
Synonyms
MUC6, MUC6_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
O-linked glycosylation (Homo sapiens)
O-linked glycosylation of mucins (Homo sapiens)
C1GALT1 transfers Galactose to the Tn antigen forming Core 1 glycoproteins (T antigens) (Homo sapiens)
Core 1 mucins [Golgi lumen] (Homo sapiens)
T-antigen (MUC6) [Golgi lumen] (Homo sapiens)
GCNTs transfer GlcNAc from UDP-GlcNAc to Core 1 mucins (Homo sapiens)
Core 1 mucins [Golgi lumen] (Homo sapiens)
T-antigen (MUC6) [Golgi lumen] (Homo sapiens)
Termination of O-glycan biosynthesis (Homo sapiens)
GalNAc alpha-2,6-sialyltransferase II can add a sialic acid to the T antigen at the alpha 6 position (Homo sapiens)
Core 1 mucins [Golgi lumen] (Homo sapiens)
T-antigen (MUC6) [Golgi lumen] (Homo sapiens)
ST3GAL1-4 can add a sialic acid to the T antigen at the alpha 3 position (Homo sapiens)
Core 1 mucins [Golgi lumen] (Homo sapiens)
T-antigen (MUC6) [Golgi lumen] (Homo sapiens)
Sialyltransferase I can add sialic acid to the T antigen at the alpha 6 position (Homo sapiens)
Core 1 mucins [Golgi lumen] (Homo sapiens)
T-antigen (MUC6) [Golgi lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6W4X9 MUC6
Gene Names
MUC6
Chain
signal peptide:1-22, chain:23-2439
Reference Genes
BioGPS Gene:4588 MUC6
COSMIC (genes):MUC6 MUC6
CTD Gene:4588 MUC6
dbSNP Gene:4588 MUC6
ENSEMBL:ENSG00000184956 MUC6
ENSEMBL:ENSG00000283350 MUC6
HGNC:7517 MUC6
KEGG Gene (Homo sapiens):4588 MUC6
Monarch:4588 MUC6
NCBI Gene:4588 MUC6
OMIM:158374 MUC6
UCSC:Q6W4X9 MUC6
Reference Transcript
RefSeq:NM_005961.2 MUC6
Other Identifiers
0003120538
0006980070
11729321_s_at
1565666_3p_s_at
1565666_s_at
16734199
214133_at
3358628
3358629
3358632
3358636
3358637
3358638
3358639
3358640
3358641
3358642
3358643
3358644
3358645
3358646
3358647
3358648
3358649
3358650
3358651
3358653
3358654
3358659
3358660
3358661
3358662
3358663
3358666
3358667
3358668
3358670
3358671
3358672
3358673
3358674
3358675
3358676
3358677
3358678
3358680
3358682
3358683
3358684
3358685
3358686
3358687
3358688
3358689
3358690
3358691
3358696
38217_at
4588
707_s_at
7945595
A_24_P88079
A_33_P3304172
GE59609
GO:0002223
GO:0002376
GO:0003674
GO:0005198
GO:0005201
GO:0005515
GO:0005575
GO:0005576
GO:0005622
GO:0005737
GO:0005794
GO:0005796
GO:0005886
GO:0006464
GO:0006950
GO:0007165
GO:0008150
GO:0009058
GO:0016266
GO:0030277
GO:0042592
GO:0043226
Hs.159593.0.S1_3p_at
Hs2.398100.1.S1_3p_s_at
ILMN_1657932
ILMN_1680070
ILMN_1683416
ILMN_1727875
ILMN_3245919
PH_hs_0024589
TC11001256.hg
TC11002987.hg
Participant Of
hasMember
Core 1 mucins [Golgi lumen]
Other forms of this molecule
Core 8 (MUC6) [Golgi lumen]
Core 2S (MUC6) [Golgi lumen]
Core 5 (MUC6) [Golgi lumen]
Core 4 (MUC6) [Golgi lumen]
Core 3 (MUC6) [Golgi lumen]
Core 7 (MUC6) [Golgi lumen]
GalNAc-MUC6(23-2392) [plasma membrane]
Core 2 (MUC6) [Golgi lumen]
Core 2a (MUC6) [Golgi lumen]
GalNAc-MUC6(23-2392) [Golgi lumen]
Sialyl Tn antigen (MUC6) [Golgi lumen]
Sialyl T-antigen (MUC6) [Golgi lumen]
Sialyl-2,3 T-antigen (MUC6) [Golgi lumen]
Disialyl T-antigen (MUC6) [Golgi lumen]
MUC6(23-2392) [Golgi lumen]
Core 6 (MUC6) [Golgi lumen]
extended Core 6 (MUC6) [Golgi lumen]
Inferred To
T-antigen (MUC6) [Golgi lumen] (Caenorhabditis elegans)
T-antigen (MUC6) [Golgi lumen] (Canis familiaris)
T-antigen (MUC6) [Golgi lumen] (Gallus gallus)
T-antigen (MUC6) [Golgi lumen] (Sus scrofa)
muc6 [Golgi lumen] (Xenopus tropicalis)
Muc6 [Golgi lumen] (Mus musculus)
Muc6 [Golgi lumen] (Rattus norvegicus)
Homologues of T-antigen (MUC6) [Golgi lumen] (Canis familiaris)
Modified Residues
Name
O-(N-acetylamino)galactosyl-L-serine (beta-D-Galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl group) at unknown position
Modification
beta-D-galactosyl-1,3-N-acetyl-alpha-D-galactosaminyl group
PsiMod Name
O-(N-acetylamino)galactosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-(N-acetylaminogalactosyl)-L-serine.
Cross References
RefSeq
NP_005952.2
OpenTargets
ENSG00000184956
HPA
ENSG00000184956-MUC6
GeneCards
Q6W4X9
Ensembl
ENSP00000490759
,
ENSG00000184956
,
ENST00000636545
,
ENSP00000406861
,
ENST00000421673
,
ENSG00000283350
PRO
Q6W4X9
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