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Core 6 (MUC4) [Golgi lumen]
Stable Identifier
R-HSA-1462274
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Golgi lumen
Synonyms
MUC4, MUC4_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
O-linked glycosylation (Homo sapiens)
O-linked glycosylation of mucins (Homo sapiens)
Addition of GlcNAc to the Tn antigen via a beta-1,6 linkage forms a Core 6 glycoprotein (Homo sapiens)
Core 6 mucins [Golgi lumen] (Homo sapiens)
Core 6 (MUC4) [Golgi lumen] (Homo sapiens)
Addition of galactose to Core 6 glycoprotein (Homo sapiens)
Core 6 mucins [Golgi lumen] (Homo sapiens)
Core 6 (MUC4) [Golgi lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q99102 MUC4
Gene Names
MUC4
Chain
signal peptide:1-28, chain:29-5412, chain:29-4687, chain:4688-5412
Reference Genes
BioGPS Gene:4585 MUC4
COSMIC (genes):MUC4 MUC4
CTD Gene:4585 MUC4
dbSNP Gene:4585 MUC4
ENSEMBL:ENSG00000145113 MUC4
ENSEMBL_homo_sapiens_GENE:ENSG00000145113.22 MUC4
HGNC:7514 MUC4
KEGG Gene (Homo sapiens):4585 MUC4
Monarch:4585 MUC4
NCBI Gene:4585 MUC4
OMIM:158372 MUC4
UCSC:Q99102 MUC4
Reference Transcript
RefSeq:NM_018406.6 MUC4
RefSeq:NM_138297.4 MUC4
RefSeq:NM_004532.5 MUC4
Other Identifiers
11751950_a_at
16963127
204895_PM_x_at
204895_x_at
217110_PM_s_at
217110_s_at
2712238
2712239
2712240
2712241
2712242
2712244
2712245
2712246
2712248
2712249
2712251
2712252
2712253
2712255
2712257
2712261
2712262
2712264
2712265
2712266
2712267
2712268
2712269
2712270
2712271
2712273
2712274
2712276
2712277
2712278
2712279
2712281
2712282
2712284
2712289
2712291
2712292
2712293
2712294
2712295
2712296
2712297
2712298
2712299
2712300
2712301
2712302
2712303
2712304
2712305
2712306
2712307
2712308
2712309
2712310
2712311
2712312
2712313
2712314
2712315
2712316
2712317
2712318
2712319
2712320
2712321
2712322
2712323
2712324
2712325
2712326
2712327
2712328
2712329
2712330
2712331
2712332
2712333
2712334
2712335
2712336
2712337
2712338
2712339
2712340
2712341
2712342
2712343
2712344
2712345
2712346
2712347
2712348
2712349
2712350
2712351
2712352
2712353
2712354
2712355
2712356
2712357
2712358
2712359
2712360
2712361
2712362
2712363
2712364
2712365
2712366
2712367
2712368
2712369
2712370
2712371
2712383
2712384
2712385
2712404
2712406
2712408
2712410
2712412
2712414
4585
734_at
8092978
A_24_P208825
A_24_P239177
A_24_P239183
A_33_P3417281
GE82366
GO:0005176
GO:0005198
GO:0005576
GO:0005615
GO:0005794
GO:0005796
GO:0005886
GO:0007155
GO:0007160
GO:0016020
GO:0022600
GO:0030197
GO:0030277
GO:0030312
GO:0031012
GO:0031982
GO:0043226
GO:0070062
HMNXSV003055737
ILMN_1727314
ILMN_1792039
ILMN_2246555
ILMN_2321153
PH_hs_0030528
TC03002150.hg
TC03003289.hg
TC03003290.hg
g11034812_3p_a_at
Participates
as a member of
Core 6 mucins [Golgi lumen] (Homo sapiens)
Other forms of this molecule
Core 8 (MUC4) [Golgi lumen]
Core 2S (MUC4) [Golgi lumen]
Core 5 (MUC4) [Golgi lumen]
Core 4 (MUC4) [Golgi lumen]
Core 3 (MUC4) [Golgi lumen]
Core 7 (MUC4) [Golgi lumen]
extended Core 6 (MUC4) [Golgi lumen]
MUC4 [Golgi lumen]
Disialyl T-antigen (MUC4) [Golgi lumen]
Sialyl T-antigen (MUC4) [Golgi lumen]
Sialyl-2,3 T-antigen (MUC4) [Golgi lumen]
T-antigen (MUC4) [Golgi lumen]
Sialyl Tn antigen (MUC4) [Golgi lumen]
GalNAc-MUC4(29-2169) [plasma membrane]
Core 2 (MUC4) [Golgi lumen]
Core 2a (MUC4) [Golgi lumen]
GalNAc-MUC4(29-2169) [Golgi lumen]
Inferred To
Muc4 [Golgi lumen]
(Mus musculus)
Muc4 [Golgi lumen]
(Rattus norvegicus)
Core 6 (MUC4) [Golgi lumen]
(Bos taurus)
Core 6 (MUC4) [Golgi lumen]
(Gallus gallus)
MUC4 [Golgi lumen]
(Canis familiaris)
MUC4 [Golgi lumen]
(Sus scrofa)
Modified Residues
Name
O-(N-acetylamino)galactosyl-L-serine (GlcNAc-beta1,6-GalNAc-alpha group) at unknown position
Modification
GlcNAc-beta1,6-GalNAc-alpha group
PsiMod Name
O-(N-acetylamino)galactosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-(N-acetylaminogalactosyl)-L-serine.
Cross References
RefSeq
NP_004523.3
,
NP_612154.2
,
NP_060876.5
OpenTargets
ENSG00000145113
HPA
ENSG00000145113-MUC4
GeneCards
Q99102
Ensembl
ENSP00000420243
,
ENST00000470451
,
ENST00000477086
,
ENST00000475231
,
ENSP00000419989
,
ENSP00000420439
,
ENSP00000419798
,
ENST00000349607
,
ENST00000478156
,
ENST00000346145
,
ENSP00000304207
,
ENSP00000338109
,
ENSG00000145113
,
ENST00000463781
,
ENSP00000417498
PRO
Q99102
Pharos - Targets
Q99102
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