Human neutrophils contain thousands of cytoplasmic granules. These membrane-bound organelles act as storage compartments destined for secretion or in the case of azurophil granules, destined for fusion with phagosomes. A small amount of defensin, but perhaps not enough for antimicrobial activity, may be released extracellularly by neutrophils (Ganz 1987).
Gullberg, U, Bengtsson, N, Bülow, E, Garwicz, D, Lindmark, A, Olsson, I
Lehrer, RI, Ganz, T
Ganz, T, Liu, L, Valore, EV, Oren, A
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