Reactome | ABCD3 [cytosol]

ABCD3 [cytosol]

Stable Identifier

R-HSA-1456459

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

ATP-binding cassette sub-family D member 3, ABCD3_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P28288 ABCD3

Gene Names

ABCD3, PMP70, PXMP1

Chain

chain:1-659

Reference Genes

BioGPS Gene:5825 ABCD3

COSMIC (genes):ABCD3 ABCD3

CTD Gene:5825 ABCD3

dbSNP Gene:5825 ABCD3

ENSEMBL:ENSG00000117528 ABCD3

HGNC:67 ABCD3

KEGG:hsa:5825 ABCD3

Monarch:5825 ABCD3

NCBI Gene:5825 ABCD3

OMIM:170995 ABCD3

UCSC:P28288 ABCD3

Reference Transcript

Other Identifiers

11720481_s_at

11741591_at

11741592_x_at

11747617_a_at

11749150_a_at

1554878_PM_a_at

1554878_a_at

16667303

202850_PM_at

202850_at

2347503

2347504

2347505

2347506

2347507

2347513

2347516

2347517

2347520

2347521

2347522

2347523

2347524

2347525

2347526

2347527

2347528

2347529

2347530

2347531

2347533

2347534

2347535

2347536

2347537

2347538

2347539

2347540

2347541

2347542

2347547

2347550

2347551

2347553

2347554

2347562

37038_at

5825

7903119

A_14_P128113

A_23_P74794

A_24_P221154

A_33_P3307955

A_33_P3307957

GE60086

GO:0000038

GO:0003824

GO:0005215

GO:0005324

GO:0005515

GO:0005524

GO:0005739

GO:0005777

GO:0005778

GO:0005782

GO:0005829

GO:0006629

GO:0006633

GO:0006635

GO:0006699

GO:0006869

GO:0007031

GO:0009410

GO:0014070

GO:0015721

GO:0015910

GO:0016020

GO:0016787

GO:0016887

GO:0042626

GO:0042760

GO:0042802

GO:0042803

GO:0043226

GO:0043231

GO:0047617

GO:0055085

GO:0140359

GO:0140657

GO:1903512

HMNXSV003042979

HMNXSV003054270

Hs2.76781.2.S1_3p_s_at

ILMN_1674032

M81182_s_at

PH_hs_0004429

TC01000872.hg

X58528_s_at

g10947125_3p_at

Participates

as a candidate of

as a member of

Class I Peroxisomal Membrane Proteins [cytosol] (Homo sapiens)

as a component of

Other forms of this molecule

ABCD3 [peroxisomal membrane]

Inferred To

ABCD3 [cytosol] (Bos taurus)

ABCD3 [cytosol] (Canis familiaris)

ABCD3 [cytosol] (Dictyostelium discoideum)

ABCD3 [cytosol] (Gallus gallus)

ABCD3 [cytosol] (Mus musculus)

ABCD3 [cytosol] (Rattus norvegicus)

ABCD3 [cytosol] (Sus scrofa)

pmp-2 [cytosol] (Caenorhabditis elegans)

Abcd3 [cytosol] (Drosophila melanogaster)

abcd3a [cytosol] (Danio rerio)

abcd3 [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_002849.1, NP_001116146.1

Guide to Pharmacology - Targets

790

ENSEMBL

ENSP00000359233, ENSP00000326880, ENST00000370214, ENSG00000117528, ENST00000315713

OpenTargets

ENSG00000117528

GeneCards

ABCD3

HPA

ENSG00000117528-ABCD3

PRO

P28288

Pharos - Targets

P28288

GlyGen

P28288

HMDB Protein

HMDBP12675

PDB

8Z0F, 8Z9X

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P40855 PEX19	1	PEX19 [cytosol] (R-HSA-3009036)	0.682	4
UniProt:P33897 ABCD1	8	ABCD1 [peroxisomal membrane] (R-HSA-382566) ABCD1 [cytosol] (R-HSA-382587) ABCD1 G277R [peroxisomal membrane] (R-HSA-5685058) ABCD1 M1V [peroxisomal membrane] (R-HSA-5685059) ABCD1 R554H [peroxisomal membrane] (R-HSA-5685072) ABCD1 S606L [peroxisomal membrane] (R-HSA-5685104) ABCD1 T77_L82del [peroxisomal membrane] (R-HSA-5685088) ABCD1 R617C [peroxisomal membrane] (R-HSA-5685069)	0.508	2
UniProt:P01116 KRAS	20	S-Farn-Me-PalmS KRAS [plasma membrane] (R-HSA-9674814) p-Y32-S-Farn-Me-PalmS KRAS [plasma membrane] (R-HSA-9674821) KRAS A146T [plasma membrane] (R-HSA-9649623) KRAS K147E [plasma membrane] (R-HSA-9651169) KRAS K147T [plasma membrane] (R-HSA-9651180) KRAS V14G [plasma membrane] (R-HSA-9651295) KRAS K147N [plasma membrane] (R-HSA-9651177) KRAS A146V [plasma membrane] (R-HSA-9649626) KRAS A146S [plasma membrane] (R-HSA-9649621) KRAS A146P [plasma membrane] (R-HSA-9649617) KRAS P34R [plasma membrane] (R-HSA-9651276) KRAS P34L [plasma membrane] (R-HSA-9651269) KRAS G12A [plasma membrane] (R-HSA-9649088) KRAS G12R [plasma membrane] (R-HSA-9649090) KRAS G13V [plasma membrane] (R-HSA-9649644) KRAS G13S [plasma membrane] (R-HSA-9649642) KRAS G13C [plasma membrane] (R-HSA-9649636) KRAS G13R [plasma membrane] (R-HSA-9649639) KRAS G13A [plasma membrane] (R-HSA-9649632) KRAS K5N [plasma membrane] (R-HSA-9651361)	0.483	2