Interaction of other adapter proteins with p-KIT

Stable Identifier
Homo sapiens
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Adapter proteins GADS, GRAP, GRB7 and GRB10 interact with activated KIT (Liu & McGlade 1998, Feng et al. 1996, Thömmes et al. 1999, Jahn et al. 2002).

Literature References
PubMed ID Title Journal Year
8647802 Grap is a novel SH3-SH2-SH3 adaptor protein that couples tyrosine kinases to the Ras pathway

Ni, J, Ouyang, YB, Feng, GS, Gentz, R, Hu, DP, Shi, ZQ

J Biol Chem 1996
9872323 Gads is a novel SH2 and SH3 domain-containing adaptor protein that binds to tyrosine-phosphorylated Shc

Liu, SK, McGlade, CJ

Oncogene 1998
10377264 Identification of Tyr-703 and Tyr-936 as the primary association sites for Grb2 and Grb7 in the c-Kit/stem cell factor receptor

Carlberg, M, Thömmes, K, Lennartsson, J, Rönnstrand, L

Biochem J 1999
11809791 Role for the adaptor protein Grb10 in the activation of Akt

Jahn, T, Duyster, J, Urschel, S, Peschel, C, Seipel, P

Mol Cell Biol 2002
16129412 Signaling by Kit protein-tyrosine kinase--the stem cell factor receptor

Roskoski, R Jr

Biochem Biophys Res Commun 2005
Orthologous Events
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