Reactome | MAOB [mitochondrial outer membrane]

MAOB [mitochondrial outer membrane]

Stable Identifier

R-HSA-141194

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial outer membrane

Synonyms

MAO-B

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P27338 MAOB

Gene Names

MAOB

Chain

initiator methionine:1, chain:2-520

Reference Genes

BioGPS Gene:4129 MAOB

COSMIC (genes):MAOB MAOB

CTD Gene:4129 MAOB

dbSNP Gene:4129 MAOB

ENSEMBL:ENSG00000069535 MAOB

HGNC:6834 MAOB

KEGG Gene (Homo sapiens):4129 MAOB

Monarch:4129 MAOB

NCBI Gene:4129 MAOB

OMIM:309860 MAOB

UCSC:P27338 MAOB

Reference Transcript

RefSeq:NM_000898.4 MAOB

Other Identifiers

0003060373

11719499_at

11750135_a_at

17110289

204041_at

37628_at

4006217

4006218

4006219

4006220

4006221

4006222

4006223

4006224

4006225

4006228

4006229

4006230

4006233

4006234

4006251

4006253

4006270

4006271

4129

8172204

A_23_P85008

A_23_P85015

GE58052

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005739

GO:0005740

GO:0005741

GO:0006091

GO:0006805

GO:0006810

GO:0007267

GO:0008131

GO:0008150

GO:0009055

GO:0009056

GO:0009058

GO:0009636

GO:0010044

GO:0010269

GO:0014063

GO:0016020

GO:0016021

GO:0016491

GO:0021762

GO:0022900

GO:0032496

GO:0034641

GO:0042135

GO:0042420

GO:0042493

GO:0042802

GO:0043167

GO:0043226

GO:0045471

GO:0045964

GO:0048545

GO:0048856

GO:0050660

GO:0050665

GO:0051412

GO:0055114

GO:0097621

HMNXSV003005857

ILMN_1727360

M69177_at

PH_hs_0029010

TC0X000978.hg

g4505092_3p_at

Participates

as a component of

MAOB:FAD [mitochondrial outer membrane] (Homo sapiens)

Inferred To

MAOB [mitochondrial outer membrane] (Dictyostelium discoideum)

MAOB [mitochondrial outer membrane] (Gallus gallus)

MAOB [mitochondrial outer membrane] (Sus scrofa)

maob [mitochondrial outer membrane] (Xenopus tropicalis)

mao [mitochondrial outer membrane] (Danio rerio)

Maob [mitochondrial outer membrane] (Mus musculus)

Maob [mitochondrial outer membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_000889.3

ZINC - World Drugs

AOFB_HUMAN

Guide to Pharmacology - Targets

2490

OpenTargets

ENSG00000069535

ZINC - FDA approved

AOFB_HUMAN

ZINC - Substances

AOFB_HUMAN

ZINC - Biogenic

AOFB_HUMAN

ZINC target

P27338

PRO

P27338

GlyGen

P27338

PDB

5MRL, 2C76, 6YT2, 2V60, 6FWC, 2V5Z, 2C67, 1OJ9, 2XFP, 1S2Q, 2V61, 2XCG, 2VRL, 6RLE, 1OJC, 2XFQ, 1S2Y, 2BK3, 1OJD, 3ZYX, 2XFU, 4CRT, 2VRM, 1S3B, 2C70, 2BK4, 2BK5, 6RKB, 1GOS, 2C64, 1H8R, 2C72, 1S3E, 6FW0, 6FVZ, 4A79, 2BYB, 2C73, 6RKP, 2C65, 3PO7, 2C66, 4A7A, 2XFN, 1OJA, 2XFO, 2C75, 2VZ2

ZINC - Investigational

AOFB_HUMAN

ZINC - Metabolites

AOFB_HUMAN

HPA

ENSG00000069535-MAOB

GeneCards

P27338

Ensembl

ENSP00000367309, ENSG00000069535, ENST00000378069

Pharos - Targets

P27338

Orphanet

24685

ZINC - Predictions - Purchasable

AOFB_HUMAN

HMDB Protein

HMDBP00161

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P21397 MAOA	2	MAOA [mitochondrial outer membrane] (R-HSA-141183) MAOA Q296* [mitochondrial outer membrane] (R-HSA-5603089)	0.564	2
UniProt:Q53GS7 GLE1	1	GLE1 [nucleoplasm] (R-HSA-8932905)	0.556	3
UniProt:P55212 CASP6	5	CASP6(24-179) [nucleoplasm] (R-HSA-352247) CASP6(194-293) [nucleoplasm] (R-HSA-352246) CASP6(24-179) [cytosol] (R-HSA-350313) CASP6(194-293) [cytosol] (R-HSA-266128) CASP6 (1-293) [cytosol] (R-HSA-6798132)	0.556	3
UniProt:P06396 GSN	7	GSN [secretory granule lumen] (R-HSA-6801486) GSN(200-270) [extracellular region] (R-HSA-976940) GSN [extracellular region] (R-HSA-6806510) GSN [ficolin-1-rich granule lumen] (R-HSA-6801465) GSN(404-782) [cytosol] (R-HSA-350272) GSN(28-403) [cytosol] (R-HSA-201618) GSN [cytosol] (R-HSA-350275)	0.556	3