Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
MAOB [mitochondrial outer membrane]
Stable Identifier
R-HSA-141194
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial outer membrane
Synonyms
MAO-B
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase I - Functionalization of compounds (Homo sapiens)
Amine Oxidase reactions (Homo sapiens)
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB (Homo sapiens)
MAOB inhibitors bind MAOB:FAD (Homo sapiens)
MAOB:FAD [mitochondrial outer membrane] (Homo sapiens)
MAOB [mitochondrial outer membrane] (Homo sapiens)
MAOB:FAD:MAOB Inhibitors [mitochondrial outer membrane] (Homo sapiens)
MAOB:FAD [mitochondrial outer membrane] (Homo sapiens)
MAOB [mitochondrial outer membrane] (Homo sapiens)
MAOB:FAD oxidatively deaminates TYR (Homo sapiens)
MAOB:FAD [mitochondrial outer membrane] (Homo sapiens)
MAOB [mitochondrial outer membrane] (Homo sapiens)
MAOB:FAD oxidatively deaminates of PEA (Homo sapiens)
MAOB:FAD [mitochondrial outer membrane] (Homo sapiens)
MAOB [mitochondrial outer membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P27338 MAOB
Gene Names
MAOB
Chain
initiator methionine:, chain:2-520
Reference Genes
BioGPS Gene:4129 MAOB
COSMIC (genes):MAOB MAOB
CTD Gene:4129 MAOB
dbSNP Gene:4129 MAOB
ENSEMBL:ENSG00000069535 MAOB
HGNC:6834 MAOB
KEGG:hsa:4129 MAOB
Monarch:4129 MAOB
NCBI Gene:4129 MAOB
OMIM:309860 MAOB
UCSC:P27338 MAOB
Reference Transcript
RefSeq:NM_000898.4 MAOB
Other Identifiers
11719499_at
11750135_a_at
17110289
204041_PM_at
204041_at
37628_at
4006217
4006218
4006219
4006220
4006221
4006222
4006223
4006224
4006225
4006228
4006229
4006230
4006233
4006234
4006251
4006253
4006254
4006255
4006256
4006270
4006271
4129
8172204
A_23_P85008
A_23_P85015
GE58052
GO:0003824
GO:0005515
GO:0005739
GO:0005740
GO:0005741
GO:0008131
GO:0009055
GO:0009410
GO:0009636
GO:0010044
GO:0010269
GO:0014063
GO:0016491
GO:0019607
GO:0021762
GO:0030425
GO:0032496
GO:0042420
GO:0042802
GO:0043025
GO:0043226
GO:0045471
GO:0045964
GO:0048545
GO:0048856
GO:0050660
GO:0050665
GO:0051412
GO:0052595
GO:0097621
HMNXSV003005857
ILMN_1727360
M69177_at
PH_hs_0029010
TC0X000978.hg
g4505092_3p_at
Participates
as a component of
MAOB:FAD [mitochondrial outer membrane] (Homo sapiens)
Inferred To
MAOB [mitochondrial outer membrane]
(Bos taurus)
MAOB [mitochondrial outer membrane]
(Canis familiaris)
MAOB [mitochondrial outer membrane]
(Gallus gallus)
MAOB [mitochondrial outer membrane]
(Sus scrofa)
maob [mitochondrial outer membrane]
(Xenopus tropicalis)
Homologues of MAOB [mitochondrial outer membrane]
(Dictyostelium discoideum)
mao [mitochondrial outer membrane]
(Danio rerio)
maoC-1 [mitochondrial outer membrane]
(Dictyostelium discoideum)
maoB-1 [mitochondrial outer membrane]
(Dictyostelium discoideum)
maoD [mitochondrial outer membrane]
(Dictyostelium discoideum)
maoA [mitochondrial outer membrane]
(Dictyostelium discoideum)
Maob [mitochondrial outer membrane]
(Mus musculus)
Maob [mitochondrial outer membrane]
(Rattus norvegicus)
Cross References
Guide to Pharmacology - Targets
2490
OpenTargets
ENSG00000069535
ENSEMBL
ENSP00000367309
,
ENST00000378069
,
ENSG00000069535
ZINC - FDA approved
AOFB_HUMAN
ZINC - Substances
AOFB_HUMAN
ZINC - Biogenic
AOFB_HUMAN
ZINC target
P27338
PRO
P27338
GlyGen
P27338
PDB
3PO7
,
6FW0
,
4A7A
,
6RKB
,
2XFO
,
1S3E
,
1S2Y
,
2XFP
,
2BYB
,
7P4F
,
7P4H
,
1S2Q
,
6RLE
,
2C64
,
2C65
,
2C67
,
2XCG
,
2BK3
,
2VRM
,
1OJA
,
2C73
,
2C75
,
2VRL
,
5MRL
,
1GOS
,
6FVZ
,
6FWC
,
2C70
,
6YT2
,
4A79
,
2XFN
,
2XFU
,
2XFQ
,
2V5Z
,
7ZW3
,
1S3B
,
7B0Z
,
7B0V
,
2C66
,
2VZ2
,
1OJD
,
6RKP
,
2V61
,
2BK4
,
2BK5
,
1OJC
,
2C72
,
2V60
,
3ZYX
,
1OJ9
,
2C76
,
4CRT
ZINC - Investigational
AOFB_HUMAN
ZINC - Metabolites
AOFB_HUMAN
HPA
ENSG00000069535-MAOB
GeneCards
MAOB
Pharos - Targets
P27338
ZINC - Predictions - Purchasable
AOFB_HUMAN
HMDB Protein
HMDBP00161
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P21397 MAOA
2
MAOA Q296* [mitochondrial outer membrane]
(R-HSA-5603089)
MAOA [mitochondrial outer membrane]
(R-HSA-141183)
0.669
3
UniProt:Q53GS7 GLE1
1
GLE1 [nucleoplasm]
(R-HSA-8932905)
0.556
3
UniProt:P06396 GSN
7
GSN [cytosol]
(R-HSA-350275)
GSN(28-403) [cytosol]
(R-HSA-201618)
GSN(404-782) [cytosol]
(R-HSA-350272)
GSN [ficolin-1-rich granule lumen]
(R-HSA-6801465)
GSN [extracellular region]
(R-HSA-6806510)
GSN [secretory granule lumen]
(R-HSA-6801486)
GSN(200-270) [extracellular region]
(R-HSA-976940)
0.556
3
UniProt:P55212 CASP6
5
CASP6(194-293) [cytosol]
(R-HSA-266128)
CASP6(24-179) [cytosol]
(R-HSA-350313)
CASP6(24-179) [nucleoplasm]
(R-HSA-352247)
CASP6(194-293) [nucleoplasm]
(R-HSA-352246)
CASP6 (1-293) [cytosol]
(R-HSA-6798132)
0.556
3
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text