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MAOB [mitochondrial outer membrane]
Stable Identifier
R-HSA-141194
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial outer membrane
Synonyms
MAO-B
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase I - Functionalization of compounds (Homo sapiens)
Amine Oxidase reactions (Homo sapiens)
Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB (Homo sapiens)
MAOB inhibitors bind MAOB:FAD (Homo sapiens)
MAOB:FAD [mitochondrial outer membrane] (Homo sapiens)
MAOB [mitochondrial outer membrane] (Homo sapiens)
MAOB:FAD:MAOB Inhibitors [mitochondrial outer membrane] (Homo sapiens)
MAOB:FAD [mitochondrial outer membrane] (Homo sapiens)
MAOB [mitochondrial outer membrane] (Homo sapiens)
MAOB:FAD oxidatively deaminates TYR (Homo sapiens)
MAOB:FAD [mitochondrial outer membrane] (Homo sapiens)
MAOB [mitochondrial outer membrane] (Homo sapiens)
MAOB:FAD oxidatively deaminates of PEA (Homo sapiens)
MAOB:FAD [mitochondrial outer membrane] (Homo sapiens)
MAOB [mitochondrial outer membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P27338 MAOB
Gene Names
MAOB
Chain
initiator methionine:1, chain:2-520
Reference Genes
BioGPS Gene:4129 MAOB
COSMIC (genes):MAOB MAOB
CTD Gene:4129 MAOB
dbSNP Gene:4129 MAOB
ENSEMBL:ENSG00000069535 MAOB
HGNC:6834 MAOB
KEGG Gene (Homo sapiens):4129 MAOB
Monarch:4129 MAOB
NCBI Gene:4129 MAOB
OMIM:309860 MAOB
UCSC:P27338 MAOB
Reference Transcript
RefSeq:NM_000898.4 MAOB
Other Identifiers
0003060373
11719499_at
11750135_a_at
17110289
204041_PM_at
204041_at
37628_at
4006217
4006218
4006219
4006220
4006221
4006222
4006223
4006224
4006225
4006228
4006229
4006230
4006233
4006234
4006251
4006253
4006270
4006271
4129
8172204
A_23_P85008
A_23_P85015
GE58052
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005739
GO:0005740
GO:0005741
GO:0006091
GO:0006810
GO:0007267
GO:0008131
GO:0008150
GO:0009055
GO:0009056
GO:0009058
GO:0009410
GO:0009636
GO:0010044
GO:0010269
GO:0014063
GO:0016020
GO:0016021
GO:0016491
GO:0021762
GO:0022900
GO:0032496
GO:0034641
GO:0042135
GO:0042420
GO:0042802
GO:0043167
GO:0043226
GO:0045471
GO:0045964
GO:0048545
GO:0048856
GO:0050660
GO:0050665
GO:0051412
GO:0097621
HMNXSV003005857
ILMN_1727360
M69177_at
PH_hs_0029010
TC0X000978.hg
g4505092_3p_at
Participates
as a component of
MAOB:FAD [mitochondrial outer membrane] (Homo sapiens)
Inferred To
MAOB [mitochondrial outer membrane]
(Bos taurus)
MAOB [mitochondrial outer membrane]
(Canis familiaris)
MAOB [mitochondrial outer membrane]
(Dictyostelium discoideum)
MAOB [mitochondrial outer membrane]
(Sus scrofa)
Maob [mitochondrial outer membrane]
(Mus musculus)
Maob [mitochondrial outer membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_000889.3
ZINC - World Drugs
AOFB_HUMAN
Guide to Pharmacology - Targets
2490
OpenTargets
ENSG00000069535
ZINC - FDA approved
AOFB_HUMAN
ZINC - Substances
AOFB_HUMAN
ZINC target
P27338
ZINC - Biogenic
AOFB_HUMAN
PRO
P27338
PDB
2XFP
,
6FW0
,
3PO7
,
2VRM
,
2C72
,
6FVZ
,
2C65
,
1S3E
,
1GOS
,
6RKB
,
4A7A
,
2XFO
,
6YT2
,
1OJ9
,
2VRL
,
4A79
,
2C66
,
6RLE
,
2XCG
,
1OJC
,
6RKP
,
1S2Y
,
3ZYX
,
6FWC
,
2XFN
,
2C76
,
2BK3
,
2XFU
,
1S2Q
,
2C67
,
2V61
,
4CRT
,
1OJA
,
2VZ2
,
2XFQ
,
5MRL
,
2C70
,
2C73
,
2C64
,
2BYB
,
2C75
,
2BK5
,
1S3B
,
2BK4
,
2V5Z
,
2V60
,
1OJD
ZINC - Investigational
AOFB_HUMAN
ZINC - Metabolites
AOFB_HUMAN
HPA
ENSG00000069535-MAOB
GeneCards
P27338
Ensembl
ENST00000378069
,
ENSP00000367309
,
ENSG00000069535
Pharos - Targets
P27338
Orphanet
24685
ZINC - Predictions - Purchasable
AOFB_HUMAN
HMDB Protein
HMDBP00161
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P21397 MAOA
2
MAOA Q296* [mitochondrial outer membrane]
(R-HSA-5603089)
MAOA [mitochondrial outer membrane]
(R-HSA-141183)
0.564
2
UniProt:P55212 CASP6
5
CASP6 (1-293) [cytosol]
(R-HSA-6798132)
CASP6(194-293) [nucleoplasm]
(R-HSA-352246)
CASP6(24-179) [nucleoplasm]
(R-HSA-352247)
CASP6(24-179) [cytosol]
(R-HSA-350313)
CASP6(194-293) [cytosol]
(R-HSA-266128)
0.556
3
UniProt:P06396 GSN
7
GSN(200-270) [extracellular region]
(R-HSA-976940)
GSN [secretory granule lumen]
(R-HSA-6801486)
GSN [extracellular region]
(R-HSA-6806510)
GSN [ficolin-1-rich granule lumen]
(R-HSA-6801465)
GSN(404-782) [cytosol]
(R-HSA-350272)
GSN(28-403) [cytosol]
(R-HSA-201618)
GSN [cytosol]
(R-HSA-350275)
0.556
3
UniProt:Q53GS7 GLE1
1
GLE1 [nucleoplasm]
(R-HSA-8932905)
0.556
3
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