factor IX -> factor IXa + factor IX activation peptide (TF:F7a catalyst)

Stable Identifier
R-HSA-140823
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
activation of factor IX (TF:F7a catalyst)
Locations in the PathwayBrowser
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Factor VIIa, bound to tissue factor at the endothelial cell surface, catalyzes the formation of activated factor IX with high efficiency. The amino terminal part of the heavy chain of factor IX, the factor IX activation peptide, is released. (This peptide has no known function.)

Literature References
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
serine-type endopeptidase activity of TF:F7a [plasma membrane]
Physical Entity
Activity
Orthologous Events
Authored
Created