Reactome | factor XIII A chain activation peptide [extracellular region]

factor XIII A chain activation peptide [extracellular region]

Stable Identifier

R-HSA-140790

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

F13A1(1-37)

Locations in the PathwayBrowser for interactor UniProt:Q96EF9 ZHX1R

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External Reference Information

External Reference

UniProt:P00488 F13A1

Gene Names

F13A1, F13A

Chain

initiator methionine:, propeptide:2-38, chain:39-732

Reference Genes

BioGPS Gene:2162 F13A1

COSMIC (genes):F13A1 F13A1

CTD Gene:2162 F13A1

dbSNP Gene:2162 F13A1

ENSEMBL:ENSG00000124491 F13A1

ENSEMBL_homo_sapiens_GENE:ENSG00000124491.16 F13A1

HGNC:3531 F13A1

KEGG Gene (Homo sapiens):2162 F13A1

Monarch:2162 F13A1

NCBI Gene:2162 F13A1

OMIM:134570 F13A1

UCSC:P00488 F13A1

Reference Transcript

RefSeq:NM_000129.3 F13A1

Other Identifiers

11716479_s_at

11752423_a_at

17015331

203305_PM_at

203305_at

2162

2940124

2940203

2940204

2940206

2940210

2940213

2940216

2940219

2940221

2940226

2940227

2940228

2940233

2940234

2940237

2940246

2940247

2940252

2940253

38052_at

8123744

A_32_P140139

A_33_P3416097

GE57829

GO:0003810

GO:0003824

GO:0005515

GO:0005576

GO:0005615

GO:0005737

GO:0007596

GO:0007599

GO:0016740

GO:0016746

GO:0018149

GO:0030312

GO:0031012

GO:0031093

GO:0031410

GO:0036211

GO:0042060

GO:0043226

GO:0046872

GO:0051604

GO:0062023

GO:0072378

GO:0072562

GO:0140096

GO:1990234

HMNXSV003023302

ILMN_1717163

M14539_at

PH_hs_0004632

TC06001246.hg

g9961355_3p_at

Participates

as an output of

factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Homo sapiens)

Other forms of this molecule

factor XIIIa A chain [extracellular region]

factor XIII A chain [extracellular region]

F13A1(1-731) [platelet alpha granule lumen]

Inferred To

factor XIII A chain activation peptide [extracellular region] (Bos taurus)

factor XIII A chain activation peptide [extracellular region] (Canis familiaris)

factor XIII A chain activation peptide [extracellular region] (Danio rerio)

factor XIII A chain activation peptide [extracellular region] (Gallus gallus)

factor XIII A chain activation peptide [extracellular region] (Mus musculus)

factor XIII A chain activation peptide [extracellular region] (Rattus norvegicus)

factor XIII A chain activation peptide [extracellular region] (Sus scrofa)

factor XIII A chain activation peptide [extracellular region] (Xenopus tropicalis)

Cross References

RefSeq

NP_000120.2

ZINC - World Drugs

F13A_HUMAN

OpenTargets

ENSG00000124491

ZINC - Substances

F13A_HUMAN

ZINC - Biogenic

F13A_HUMAN

ZINC target

P00488

PRO

P00488

PDB

5MHN, 1EVU, 1QRK, 1EX0, 1GGY, 5MHO, 4KTY, 5MHL, 1GGT, 1F13, 1GGU, 5MHM, 1FIE

ZINC - Metabolites

F13A_HUMAN

GeneCards

P00488

HPA

ENSG00000124491-F13A1

Ensembl

ENSG00000124491, ENSP00000264870, ENST00000264870

Pharos - Targets

P00488

Orphanet

16011

ZINC - Predictions - Purchasable

F13A_HUMAN

HMDB Protein

HMDBP00672

Interactors (25)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96EF9 ZHX1R			0.556	3
UniProt:Q96GL9 F163A			0.556	3
UniProt:O60636 TSN2			0.556	3
IntAct:EBI-25852833 CCSB			0.556	3
UniProt:Q9NZC7-5 WWOX			0.556	3
UniProt:O15273 TCAP	1	TCAP [cytosol] (R-HSA-390571)	0.556	3
UniProt:Q9Y2M5 KLHL20	1	KLHL20 [cytosol] (R-HSA-976032)	0.556	3
UniProt:Q6NXG1-3 Q6NXG13			0.556	3
UniProt:P19388 POLR2E	2	POLR2E [nucleoplasm] (R-HSA-83713) POLR2E [cytosol] (R-HSA-1964438)	0.556	3
UniProt:O60830 TIMM17B	2	TIMM17B [mitochondrial intermembrane space] (R-HSA-1955371) TIMM17B [mitochondrial inner membrane] (R-HSA-1252138)	0.556	3
UniProt:Q6ZMI0-5 PPP1R21			0.556	3
UniProt:Q14005-2 Q140052			0.556	3
UniProt:Q9BXL8 CDCA4			0.556	3
UniProt:Q7Z783 Q7Z783			0.556	3
UniProt:Q8WXK3-2 ASB13			0.556	3
UniProt:Q8WZ73-3 Q8WZ733			0.556	3
UniProt:Q99944 EGFL8			0.556	3
IntAct:EBI-25835866 CCSB			0.556	3
UniProt:Q2NKQ1-4 SGSM1			0.556	3
UniProt:Q8IUR5-4 TMTC1			0.556	3
UniProt:Q6NXG1 ESRP1	3	ESRP1 [nucleoplasm] (R-HSA-6803472) ESRP1(1-606)-p-RAF1(227-648) fusion [cytosol] (R-HSA-6802523) ESRP1(1-606)-RAF1(227-648) fusion [cytosol] (R-HSA-6802312)	0.556	3
UniProt:Q6DKI2 LEG9C			0.556	3
UniProt:Q96MX0 CKLF3			0.556	3
UniProt:Q6P4D5-2 PABIR3			0.556	3
UniProt:P0DTD1-PRO_0000449633 REP			0.488	2

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