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sequestered tissue factor [plasma membrane]
Stable Identifier
R-HSA-140762
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
F3
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Formation of Fibrin Clot (Clotting Cascade) (Homo sapiens)
Extrinsic Pathway of Fibrin Clot Formation (Homo sapiens)
sequestered tissue factor -> tissue factor (Homo sapiens)
sequestered tissue factor [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by NTRKs (Homo sapiens)
Signaling by NTRK1 (TRKA) (Homo sapiens)
Nuclear Events (kinase and transcription factor activation) (Homo sapiens)
NGF-stimulated transcription (Homo sapiens)
TF gene expression (Homo sapiens)
sequestered tissue factor [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P13726 TF
Gene Names
TF, F3
Chain
signal peptide:1-32, chain:33-295
Reference Genes
BioGPS Gene:2152 TF
COSMIC (genes):F3 TF
COSMIC (genes):TF TF
CTD Gene:2152 TF
dbSNP Gene:2152 TF
ENSEMBL:ENSG00000117525 TF
HGNC:3541 TF
KEGG:hsa:2152 TF
Monarch:2152 TF
NCBI Gene:2152 TF
OMIM:134390 TF
UCSC:P13726 TF
Reference Transcript
RefSeq:NM_001993.4 TF
RefSeq:NM_001178096.1 TF
Other Identifiers
11721290_a_at
11721291_a_at
11755733_a_at
16689869
204363_PM_at
204363_at
2152
2423910
2423911
2423912
2423913
2423914
2423915
2423916
2423918
2423919
2423920
2423922
2423923
2423924
2423928
2423929
2423933
2423934
2423935
36543_at
7917875
A_23_P126782
A_33_P3226832
GE475336
GE57466
GE63077
GO:0001938
GO:0002020
GO:0002541
GO:0002543
GO:0003824
GO:0004252
GO:0004896
GO:0005515
GO:0005543
GO:0005576
GO:0005615
GO:0005886
GO:0006919
GO:0007596
GO:0008289
GO:0009897
GO:0009986
GO:0010628
GO:0010641
GO:0016020
GO:0016485
GO:0016787
GO:0019221
GO:0030312
GO:0030335
GO:0031012
GO:0032008
GO:0032757
GO:0045766
GO:0050927
GO:0051604
GO:0060089
GO:0062023
GO:0140096
GO:1905286
HMNXSV003048205
ILMN_1797009
M27436_s_at
PH_hs_0003939
TC01002886.hg
g10518499_3p_at
Participates
as an input of
sequestered tissue factor -> tissue factor (Homo sapiens)
as an output of
TF gene expression (Homo sapiens)
Other forms of this molecule
PalmC, 2HC-F3 [plasma membrane]
Inferred To
F3 [plasma membrane]
(Bos taurus)
F3 [plasma membrane]
(Canis familiaris)
F3 [plasma membrane]
(Mus musculus)
F3 [plasma membrane]
(Rattus norvegicus)
F3 [plasma membrane]
(Sus scrofa)
f3a [plasma membrane]
(Danio rerio)
sequestered tissue factor [plasma membrane]
(Gallus gallus)
Cross References
RefSeq
NP_001171567.1
,
NP_001984.1
Guide to Pharmacology - Targets
3192
OpenTargets
ENSG00000117525
ENSEMBL
ENST00000334047
,
ENST00000370207
,
ENSP00000334145
,
ENSP00000359226
ZINC - Substances
TF_HUMAN
ZINC - Biogenic
TF_HUMAN
ZINC target
P13726
PRO
P13726
PDB
2FLB
,
5W06
,
1WSS
,
2C4F
,
1BOY
,
4M7L
,
8CN9
,
2EC9
,
2A2Q
,
1UJ3
,
1W2K
,
2FIR
,
2ZP0
,
4IBL
,
2B7D
,
4YLQ
,
4Z6A
,
1WV7
,
1Z6J
,
6Z9W
,
2AEI
,
1WTG
,
2ZWL
,
4ZMA
,
3TH3
,
2CFJ
,
2HFT
,
1J9C
,
1DAN
,
2FLR
,
1O5D
,
1W0Y
,
1WQV
,
3ELA
,
1FAK
,
1JPS
,
2CEZ
,
2PUQ
,
1TFH
,
6R2W
,
2F9B
,
1AHW
,
2AER
,
2B8O
,
3TH2
,
1WUN
,
2ZZU
,
2CEH
,
2CEF
,
3TH4
ZINC - Investigational
TF_HUMAN
HPA
ENSG00000117525-F3
Pharos - Targets
P13726
ZINC - Predictions - Purchasable
TF_HUMAN
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P08709 F7
11
factor VIIa heavy chain [plasma membrane]
(R-HSA-140724)
10xCbxE-F7(61-212) [plasma membrane]
(R-HSA-140715)
factor VIIa heavy chain [extracellular region]
(R-HSA-140750)
10xCbxE-F7(61-212) [extracellular region]
(R-HSA-140749)
10xCbxE-F7(61-466) [extracellular region]
(R-HSA-140771)
10xCbxE-F7(61-466) [plasma membrane]
(R-HSA-140774)
F7(21-466) [endoplasmic reticulum lumen]
(R-HSA-159848)
10xCbxE-F7(21-466) [endoplasmic reticulum lumen]
(R-HSA-159722)
pro-factor VII [Golgi lumen]
(R-HSA-159767)
factor VII [Golgi lumen]
(R-HSA-159808)
factor VII propeptide [Golgi lumen]
(R-HSA-159847)
0.881
7
UniProt:Q92544 TM9S4
0.564
2
UniProt:Q9UM19 HPCL4
0.556
3
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