Activated thrombin (factor IIa) catalyzes the conversion of factor V to factor Va (activated factor V). The activation peptide released in this reaction has no known function.
Butenas, S, Xu, H, Orfeo, T, Nesheim, ME, Brufatto, N, Mann, KG
serine-type endopeptidase activity of activated thrombin (factor IIa) [extracellular region]
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