Translocation of activated BAD protein to mitochondria

Stable Identifier
R-HSA-139905
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol, mitochondrial outer membrane
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Translocation of activated BAD protein to mitochondria
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Dephosphorylated BAD translocates to the outer mitochondrial membrane (Wang et al. 1999).

Literature References
PubMed ID Title Journal Year
10195903 Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD

Wang, HG, Pathan, N, Ethell, IM, Krajewski, S, Yamaguchi, Y, Shibasaki, F, McKeon, F, Bobo, T, Franke, TF, Reed, JC

Science 1999
Participants
Input
Output
Participant Of
hasEvent
Event Information
Go Biological Process
protein insertion into mitochondrial membrane involved in apoptotic signaling pathway (0001844)
Orthologous Events
Translocation of activated BAD protein to mitochondria (Bos taurus)
Translocation of activated BAD protein to mitochondria (Canis familiaris)
Translocation of activated BAD protein to mitochondria (Danio rerio)
Translocation of activated BAD protein to mitochondria (Mus musculus)
Translocation of activated BAD protein to mitochondria (Rattus norvegicus)
Translocation of activated BAD protein to mitochondria (Sus scrofa)
Translocation of activated BAD protein to mitochondria (Xenopus tropicalis)
Created
Hardwick, JM  (2004-08-09)
Tsujimoto, Y  (2004-08-09)