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PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane]
Stable Identifier
R-HSA-1369085
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Prolactin receptor signaling (Homo sapiens)
PRLR binds SCF beta-TrCP complex (Homo sapiens)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane] (Homo sapiens)
Prolactin receptor is internalized (Homo sapiens)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane] (Homo sapiens)
Prolactin receptor ligands bind the prolactin receptor (Homo sapiens)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane] (Homo sapiens)
Participants
components
BTRC:CUL1:RBX1:SKP1 [cytosol]
(Homo sapiens)
PRLR ligands:p-S349-PRLR:JAK2 dimer [plasma membrane]
(Homo sapiens)
Participates
as an input of
Prolactin receptor is internalized (Homo sapiens)
as an output of
PRLR binds SCF beta-TrCP complex (Homo sapiens)
This entity regulates
Negatively
Prolactin receptor ligands bind the prolactin receptor
(Homo sapiens)
Inferred To
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane]
(Canis familiaris)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane]
(Gallus gallus)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane]
(Mus musculus)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane]
(Rattus norvegicus)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane]
(Sus scrofa)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane]
(Xenopus tropicalis)
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