Reactome | ABCB10 [mitochondrial inner membrane]

ABCB10 [mitochondrial inner membrane]

Stable Identifier

R-HSA-1369015

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

mABC2, ATP-binding cassette sub-family B member 10, mitochondrial, ABCBA_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9NRK6 ABCB10

Gene Names

ABCB10

Chain

transit peptide:1-105, chain:106-738

Reference Genes

BioGPS Gene:23456 ABCB10

COSMIC (genes):ABCB10 ABCB10

CTD Gene:23456 ABCB10

dbSNP Gene:23456 ABCB10

ENSEMBL:ENSG00000135776 ABCB10

ENSEMBL_homo_sapiens_GENE:ENSG00000135776.5 ABCB10

HGNC:41 ABCB10

KEGG Gene (Homo sapiens):23456 ABCB10

Monarch:23456 ABCB10

NCBI Gene:23456 ABCB10

OMIM:605454 ABCB10

UCSC:Q9NRK6 ABCB10

Reference Transcript

RefSeq:NM_012089.2 ABCB10

Other Identifiers

11724634_s_at

16700324

223320_PM_s_at

223320_s_at

23456

2459925

2459926

2459927

2459928

2459929

2459930

2459933

2459936

2459940

2459941

2459944

2459945

2459949

2459950

2459952

2459954

2459956

2459960

2459961

2459962

2459963

2459964

35458_r_at

3585627

3585630

3585634

3585635

3585638

3585640

3585642

3585644

3613120

3613121

3613122

3613124

3613125

3613129

3613131

3613132

3615145

3615147

3615150

3615151

3615155

3615157

3615160

3615163

4038853

4038854

4038856

4038857

4038860

4038862

4038865

4038866

4038867

59294_at

7924956

A_23_P201918

A_24_P274073

GE58975

GO:0000166

GO:0002376

GO:0003824

GO:0005215

GO:0005515

GO:0005524

GO:0005739

GO:0005743

GO:0006783

GO:0006839

GO:0016020

GO:0016787

GO:0016887

GO:0030154

GO:0031966

GO:0034514

GO:0042802

GO:0042803

GO:0043226

GO:0045648

GO:0046985

GO:0048821

GO:0048856

GO:0055085

GO:0070455

GO:0140359

GO:0140657

HMNXSV003052873

ILMN_1665730

PH_hs_0027535

TC01003949.hg

U18237_at

g12751097_3p_a_at

g12751097_3p_x_at

Participates

as a component of

mABC2 dimer [mitochondrial inner membrane] (Homo sapiens)

Inferred To

EG:171D11.2 [mitochondrial inner membrane] (Drosophila melanogaster)

Cross References

RefSeq

NP_036221.2

Guide to Pharmacology - Targets

777

OpenTargets

ENSG00000135776

GeneCards

Q9NRK6

HPA

ENSG00000135776-ABCB10

Ensembl

ENSG00000135776, ENST00000344517, ENSP00000355637

PRO

Q9NRK6

Pharos - Targets

Q9NRK6

HMDB Protein

HMDBP08628

PDB

7Y49, 7Y48, 4AYT, 4AYW, 4AYX, 3ZDQ

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	6