Expression of PPARGC1A (PGC-1alpha)

Stable Identifier
R-HSA-1368140
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Expression of PPARGC1A (PGC-1alpha)
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

The PPARGC1A (PGC-1alpha) gene is transcribed to yield mRNA and the mRNA is translated to yield protein. PPARGC1A protein is located in the nucleus where it coactivates transcription.

Literature References
PubMed ID Title Journal Year
10713165 A tissue-specific coactivator of steroid receptors, identified in a functional genetic screen

Knutti, D, Kaul, A, Kralli, A

Mol Cell Biol 2000
12563009 Exercise induces transient transcriptional activation of the PGC-1alpha gene in human skeletal muscle

Pilegaard, H, Saltin, B, Neufer, PD

J Physiol 2003
10643692 Cloning and mRNA tissue distribution of human PPARgamma coactivator-1

Larrouy, D, Vidal, H, Andreelli, F, Laville, M, Langin, D

Int J Obes Relat Metab Disord 1999
Participants
Input
Output
Participant Of
hasEvent
This event is regulated
Negatively by
Positively by
Authored
May, B  (2011-06-22)
Reviewed
Lezza, AM  (2013-12-07)
Created
May, B  (2011-06-30)