FXN:ISD11:NFS1:ISCU [mitochondrial matrix]

Stable Identifier
R-HSA-1362404
Type
Complex
Species
Homo sapiens
Compartment
mitochondrial matrix
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
21298097 Mammalian frataxin: an essential function for cellular viability through an interaction with a preformed ISCU/NFS1/ISD11 iron-sulfur assembly complex

Reutenauer, L, Puccio, H, Colin, F, Schmucker, S, Wattenhofer-Donzé, M, Martelli, A, Page, A

PLoS One 2011
20873749 Human frataxin is an allosteric switch that activates the Fe-S cluster biosynthetic complex

Tsai, CL, Barondeau, DP

Biochemistry 2010
11060020 Distinct iron-sulfur cluster assembly complexes exist in the cytosol and mitochondria of human cells

Tong, WH, Rouault, TA

EMBO J 2000
17331979 Mitochondrial frataxin interacts with ISD11 of the NFS1/ISCU complex and multiple mitochondrial chaperones

Shan, Y, Napoli, E, Cortopassi, G

Hum Mol Genet 2007
Participants
components
Participates
as an input of
Inferred To
FXN:ISD11:NFS1:ISCU [mitochondrial matrix] (Bos taurus)
FXN:ISD11:NFS1:ISCU [mitochondrial matrix] (Caenorhabditis elegans)
FXN:ISD11:NFS1:ISCU [mitochondrial matrix] (Canis familiaris)
FXN:ISD11:NFS1:ISCU [mitochondrial matrix] (Danio rerio)
FXN:ISD11:NFS1:ISCU [mitochondrial matrix] (Dictyostelium discoideum)
FXN:ISD11:NFS1:ISCU [mitochondrial matrix] (Drosophila melanogaster)
FXN:ISD11:NFS1:ISCU [mitochondrial matrix] (Gallus gallus)
FXN:ISD11:NFS1:ISCU [mitochondrial matrix] (Mus musculus)
FXN:ISD11:NFS1:ISCU [mitochondrial matrix] (Plasmodium falciparum)
FXN:ISD11:NFS1:ISCU [mitochondrial matrix] (Rattus norvegicus)
FXN:ISD11:NFS1:ISCU [mitochondrial matrix] (Saccharomyces cerevisiae)
FXN:ISD11:NFS1:ISCU [mitochondrial matrix] (Schizosaccharomyces pombe)
FXN:ISD11:NFS1:ISCU [mitochondrial matrix] (Sus scrofa)
FXN:ISD11:NFS1:ISCU [mitochondrial matrix] (Xenopus tropicalis)
Cross References
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