FXN:ISD11:NFS1:ISCU [mitochondrial matrix]

Stable Identifier
Homo sapiens
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
20873749 Human frataxin is an allosteric switch that activates the Fe-S cluster biosynthetic complex

Tsai, CL, Barondeau, DP

Biochemistry 2010
21298097 Mammalian frataxin: an essential function for cellular viability through an interaction with a preformed ISCU/NFS1/ISD11 iron-sulfur assembly complex

Schmucker, S, Martelli, A, Colin, F, Page, A, Wattenhofer-Donzé, M, Reutenauer, L, Puccio, H

PLoS One 2011
11060020 Distinct iron-sulfur cluster assembly complexes exist in the cytosol and mitochondria of human cells

Tong, WH, Rouault, TA

EMBO J 2000
17331979 Mitochondrial frataxin interacts with ISD11 of the NFS1/ISCU complex and multiple mitochondrial chaperones

Shan, Y, Napoli, E, Cortopassi, G

Hum Mol Genet 2007
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