Reactome | TRIAP1 [mitochondrial intermembrane space]

TRIAP1 [mitochondrial intermembrane space]

Stable Identifier

R-HSA-1307778

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial intermembrane space

Synonyms

TP53-regulated inhibitor of apoptosis 1, TRIA1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O43715 TRIAP1

Gene Names

TRIAP1, 15E1.1, HSPC132

Chain

chain:1-76

Reference Genes

BioGPS Gene:51499 TRIAP1

COSMIC (genes):TRIAP1 TRIAP1

CTD Gene:51499 TRIAP1

dbSNP Gene:51499 TRIAP1

ENSEMBL:ENSG00000170855 TRIAP1

ENSEMBL:ENSG00000170855.4 TRIAP1

HGNC:26937 TRIAP1

KEGG Gene (Homo sapiens):51499 TRIAP1

Monarch:51499 TRIAP1

NCBI Gene:51499 TRIAP1

OMIM:614943 TRIAP1

UCSC:O43715 TRIAP1

Reference Transcript

RefSeq:NM_016399.2 TRIAP1

Other Identifiers

11718280_s_at

16771303

218403_PM_at

218403_at

32955_at

3474496

3474497

3474499

3474500

51499

54093_at

7967056

A_23_P128408

GE58729

GO:0000278

GO:0002039

GO:0005215

GO:0005515

GO:0005634

GO:0005654

GO:0005739

GO:0005758

GO:0006351

GO:0006355

GO:0006869

GO:0006915

GO:0006977

GO:0007005

GO:0012501

GO:0015914

GO:0023052

GO:0030330

GO:0032991

GO:0034644

GO:0043066

GO:0043154

GO:0043226

GO:0045332

GO:0045944

GO:0061024

GO:0090201

GO:0097035

GO:0120009

GO:1902166

GO:1990050

GO:2001140

HMNXSV003031668

ILMN_1774083

PH_hs_0004104

TC12002044.hg

g7705466_3p_at

Participates

as an output of

TP53 stimulates TRIAP1 expression (Homo sapiens)

as a component of

TRIAP1:PRELID1, PRELID3A [mitochondrial intermembrane space] (Homo sapiens)

as an input of

TRIAP1 binds PRELID1, PRELID3A (Homo sapiens)

Inferred To

Triap1 [mitochondrial intermembrane space] (Mus musculus)

Triap1 [mitochondrial intermembrane space] (Rattus norvegicus)

Dmel\CG30109 [mitochondrial intermembrane space] (Drosophila melanogaster)

TRIAP1 [mitochondrial intermembrane space] (Bos taurus)

TRIAP1 [mitochondrial intermembrane space] (Canis familiaris)

TRIAP1 [mitochondrial intermembrane space] (Dictyostelium discoideum)

TRIAP1 [mitochondrial intermembrane space] (Gallus gallus)

TRIAP1 [mitochondrial intermembrane space] (Plasmodium falciparum)

TRIAP1 [mitochondrial intermembrane space] (Schizosaccharomyces pombe)

TRIAP1 [mitochondrial intermembrane space] (Sus scrofa)

MDM35 [mitochondrial intermembrane space] (Saccharomyces cerevisiae)

triap1 [mitochondrial intermembrane space] (Xenopus tropicalis)

zgc:112025 [mitochondrial intermembrane space] (Danio rerio)

Cross References

RefSeq

NP_057483.1

OpenTargets

ENSG00000170855

HPA

ENSG00000170855-TRIAP1

GeneCards

O43715

Ensembl

ENST00000546954, ENSP00000449795, ENSG00000170855

PRO

O43715

Pharos - Targets

O43715

PDB

8AG0, 4XZV, 6I4Y, 6I3V, 4XZS, 6I3Y

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P80188 LCN2	2	LCN2 [specific granule lumen] (R-HSA-6799614) LCN2 [extracellular region] (R-HSA-5215934)	0.556	3
UniProt:Q9H8W4 PKHF2			0.556	3
UniProt:Q9Y255 PRELID1	1	PRELID1 [mitochondrial intermembrane space] (R-HSA-6801215)	0.527	5
UniProt:Q9Y3B1 PLD3B			0.527	5

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