GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers

Stable Identifier
R-HSA-1306969
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol, extracellular region, plasma membrane
ReviewStatus
5/5
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GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers
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GRB2:SOS1 complex binds to phosphorylated tyrosine residue Y1139 of ERBB2 in complex with ERBB4.

Literature References
PubMed ID Title Journal Year
8622888 Signal transduction pathways induced by heregulin in MDA-MB-453 breast cancer cells

Cho, C, Sepp-Lorenzino, L, Lupu, R, Eberhard, I, Ma, Z, Serve, H, Liu, F, Rosen, N

Oncogene 1996
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as an event of
Orthologous Events
GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers (Bos taurus)
GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers (Canis familiaris)
GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers (Drosophila melanogaster)
GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers (Gallus gallus)
GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers (Mus musculus)
GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers (Rattus norvegicus)
GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers (Sus scrofa)
GRB2:SOS1 complex binds phosphorylated ERBB4:ERBB2 heterodimers (Xenopus tropicalis)
Authored
Orlic-Milacic, M  (2011-11-04)
Reviewed
Neckers, LM  (2011-11-11)
Xu, W  (2011-11-11)
Created
Orlic-Milacic, M  (2011-05-28)
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