TWIK related potassium channel (TREK)

Stable Identifier
R-HSA-1299503
Type
Pathway
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this pathway in the Pathway Browser

TREK1 and TREK 2 are activated by physiochemical changes like stretch, convex deformation of the plasma membrane, depolarization, heat and intracellular acidosis. Polyunsaturated fatty acids (PUFA) including arachidonic acid open TREK channels.

Literature References
PubMed ID Title Journal Year
19840997 AMP-activated protein kinase inhibits TREK channels

Kréneisz, O, Benoit, JP, Bayliss, DA, Mulkey, DK

J Physiol 2009
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created
Cite Us!