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LDHD(?-507) [mitochondrial inner membrane]
Stable Identifier
R-HSA-1299433
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial inner membrane
Synonyms
LDHD, Probable D-lactate dehydrogenase, mitochondrial, LDHD_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Mitochondrial protein degradation (Homo sapiens)
LONP1 binds mitochondrial inner membrane proteins (Homo sapiens)
LONP1:substrate protein (mitochondrial inner membrane) [mitochondrial matrix] (Homo sapiens)
Substrate of LONP1 (mitochondrial inner membrane) [mitochondrial inner membrane] (Homo sapiens)
LDHD(?-507) [mitochondrial inner membrane] (Homo sapiens)
Substrate of LONP1 (mitochondrial inner membrane) [mitochondrial inner membrane] (Homo sapiens)
LDHD(?-507) [mitochondrial inner membrane] (Homo sapiens)
LONP1 degrades mitochondrial inner membrane proteins (Homo sapiens)
LONP1:substrate protein (mitochondrial inner membrane) [mitochondrial matrix] (Homo sapiens)
Substrate of LONP1 (mitochondrial inner membrane) [mitochondrial inner membrane] (Homo sapiens)
LDHD(?-507) [mitochondrial inner membrane] (Homo sapiens)
Protein localization (Homo sapiens)
Mitochondrial protein import (Homo sapiens)
MPP cleaves targeting peptide (presequence) of inner membrane precursors (Homo sapiens)
TIMM23 SORT:Cargo [mitochondrial inner membrane] (Homo sapiens)
Cargo of TIMM23 SORT [mitochondrial inner membrane] (Homo sapiens)
LDHD(?-507) [mitochondrial inner membrane] (Homo sapiens)
TIMM23 SORT inserts proteins into inner membrane (Homo sapiens)
Cargo of TIMM23 SORT [mitochondrial inner membrane] (Homo sapiens)
LDHD(?-507) [mitochondrial inner membrane] (Homo sapiens)
TIMM23 SORT:Cargo [mitochondrial inner membrane] (Homo sapiens)
Cargo of TIMM23 SORT [mitochondrial inner membrane] (Homo sapiens)
LDHD(?-507) [mitochondrial inner membrane] (Homo sapiens)
General
The N-terminus of LDLD is predicted by software.
Literature References
PubMed ID
Title
Journal
Year
12127981
Identification of putative mammalian D-lactate dehydrogenase enzymes
Konieczny, SF
,
Flick, MJ
Biochem Biophys Res Commun
2002
External Reference Information
External Reference
UniProt:Q86WU2 DLD
Gene Names
DLD, LDHD
Chain
transit peptide:1-52, chain:53-507
Reference Genes
BioGPS Gene:197257 DLD
COSMIC (genes):DLD DLD
CTD Gene:197257 DLD
dbSNP Gene:197257 DLD
ENSEMBL:ENSG00000166816 DLD
ENSEMBL_homo_sapiens_GENE:ENSG00000166816.15 DLD
HGNC:19708 DLD
KEGG Gene (Homo sapiens):197257 DLD
Monarch:197257 DLD
NCBI Gene:197257 DLD
OMIM:607490 DLD
UCSC:Q86WU2 DLD
Reference Transcript
RefSeq:NM_153486.3 DLD
RefSeq:NM_194436.2 DLD
Other Identifiers
11726884_a_at
16828400
197257
229241_PM_at
229241_at
3699343
3699344
3699345
3699346
3699348
3699351
3699353
3699354
3699356
3699357
3699360
3699361
3699364
3699366
3699367
3699368
3699370
3699371
63569_at
8002830
A_23_P54918
GE52971
GO:0003824
GO:0004458
GO:0005515
GO:0005739
GO:0005743
GO:0008720
GO:0016491
GO:0043226
GO:0050660
GO:0071949
GO:1903457
HMNXSV003048556
Hs.21798.0.A1_3p_at
ILMN_1722771
ILMN_2407346
PH_hs_0029965
TC16001274.hg
Participates
as a member of
Substrate of LONP1 (mitochondrial inner membrane) [mitochondrial inner membrane] (Homo sapiens)
as a candidate of
Cargo of TIMM23 SORT [mitochondrial inner membrane] (Homo sapiens)
Other forms of this molecule
LDHD(1-507) [mitochondrial intermembrane space]
LDHD(1-507) [mitochondrial inner membrane]
LDHD(1-?) [mitochondrial matrix]
Inferred To
Ldhd [mitochondrial inner membrane]
(Mus musculus)
Ldhd [mitochondrial inner membrane]
(Rattus norvegicus)
LDHD(?-507) [mitochondrial inner membrane]
(Caenorhabditis elegans)
LDHD(?-507) [mitochondrial inner membrane]
(Dictyostelium discoideum)
DLD1 [mitochondrial inner membrane]
(Saccharomyces cerevisiae)
LDHD [mitochondrial inner membrane]
(Bos taurus)
LDHD [mitochondrial inner membrane]
(Canis familiaris)
LDHD [mitochondrial inner membrane]
(Sus scrofa)
Cross References
RefSeq
NP_919417.1
,
NP_705690.2
OpenTargets
ENSG00000091140
IntEnz
1.1.2.4
GeneCards
Q86WU2
HPA
ENSG00000166816-LDHD
Ensembl
ENSP00000300051
,
ENST00000450168
,
ENSP00000417011
,
ENST00000300051
,
ENSG00000166816
PRO
Q86WU2
Pharos - Targets
Q86WU2
HMDB Protein
HMDBP03582
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