Activation of TRESK

Stable Identifier
R-HSA-1299338
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
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TRESK is expressed in spinal cord and brain and is involved in K+ efflux. TRESK activation may be mediated by calcineurin.

Literature References
PubMed ID Title Journal Year
20871611 A dominant-negative mutation in the TRESK potassium channel is linked to familial migraine with aura

Lafrenière, RG, Cader, MZ, Poulin, JF, Andres-Enguix, I, Simoneau, M, Gupta, N, Boisvert, K, Lafrenière, F, McLaughlan, S, Dubé, MP, Marcinkiewicz, MM, Ramagopalan, S, Ansorge, O, Brais, B, Sequeiros, J, Pereira-Monteiro, JM, Griffiths, LR, Tucker, SJ, Ebers, G, Rouleau, GA

Nat Med 2010
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
potassium channel activity of TRESK homodimer [plasma membrane]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
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