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Tandem pore domain halothane-inhibited K+ channel (THIK)
Stable Identifier
R-HSA-1299287
Type
Pathway
Species
Homo sapiens
Compartment
plasma membrane
,
cytosol
,
extracellular region
ReviewStatus
5/5
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Neuronal System (Homo sapiens)
Potassium Channels (Homo sapiens)
Tandem pore domain potassium channels (Homo sapiens)
Tandem pore domain halothane-inhibited K+ channel (THIK) (Homo sapiens)
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THIK channels are K+ leak channels that are not regulated by pH or temperature changes.
Literature References
PubMed ID
Title
Journal
Year
16683720
Acute hypoxic regulation of recombinant THIK-1 stably expressed in HEK293 cells
Brown, ST
,
Hudasek, K
,
Campanucci, VA
,
O'Kelly, IM
,
Fearon, IM
,
Nurse, CA
Adv Exp Med Biol
2006
Participants
Events
Activation of THIK
(Homo sapiens)
Participates
as an event of
Tandem pore domain potassium channels (Homo sapiens)
Event Information
Go Biological Process
potassium ion transmembrane transport (0071805)
Orthologous Events
Tandem pore domain halothane-inhibited K+ channel (THIK) (Bos taurus)
Tandem pore domain halothane-inhibited K+ channel (THIK) (Caenorhabditis elegans)
Tandem pore domain halothane-inhibited K+ channel (THIK) (Canis familiaris)
Tandem pore domain halothane-inhibited K+ channel (THIK) (Danio rerio)
Tandem pore domain halothane-inhibited K+ channel (THIK) (Gallus gallus)
Tandem pore domain halothane-inhibited K+ channel (THIK) (Mus musculus)
Tandem pore domain halothane-inhibited K+ channel (THIK) (Rattus norvegicus)
Tandem pore domain halothane-inhibited K+ channel (THIK) (Saccharomyces cerevisiae)
Tandem pore domain halothane-inhibited K+ channel (THIK) (Sus scrofa)
Authored
Mahajan, SS (2011-05-23)
Reviewed
Jassal, B (2010-09-23)
Created
Mahajan, SS (2011-05-23)
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