Association of ADAM and B4GALT1 With ZP3

Stable Identifier
R-HSA-1297338
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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In humans induction of acrosome reaction is mediated by ADAM and B4GALT1 binding to ZP3 and ZP4. Binding of ZP3 to its putative sperm receptor zona receptor kinase, leads to its aggregation and downstream cAMP signaling.

Literature References
PubMed ID Title Journal Year
20364096 Fertilization: a sperm's journey to and interaction with the oocyte

Ikawa, M, Inoue, N, Benham, AM, Okabe, M

J Clin Invest 2010
Participants
Participant Of
Event Information
Orthologous Events
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