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KCNK4 [plasma membrane]
Stable Identifier
R-HSA-1296325
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Potassium channel subfamily K member 4 (TRAAK), KCNK4_HUMAN
Locations in the PathwayBrowser
Expand all
Muscle contraction (Homo sapiens)
Cardiac conduction (Homo sapiens)
Phase 4 - resting membrane potential (Homo sapiens)
KCNK dimers transport K+ from cytosol to extracellular region (Homo sapiens)
KCNK dimers [plasma membrane] (Homo sapiens)
KCNK4 dimer [plasma membrane] (Homo sapiens)
KCNK4 [plasma membrane] (Homo sapiens)
Neuronal System (Homo sapiens)
Potassium Channels (Homo sapiens)
Tandem pore domain potassium channels (Homo sapiens)
TWIK related potassium channel (TREK) (Homo sapiens)
Activation of TWIK-related K+ channel (TREK) (Homo sapiens)
TREK homodimers [plasma membrane] (Homo sapiens)
TREK members [plasma membrane] (Homo sapiens)
KCNK4 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NYG8 KCNK4
Gene Names
KCNK4, TRAAK
Chain
chain:1-393
Reference Genes
BioGPS Gene:50801 KCNK4
COSMIC (genes):KCNK4 KCNK4
CTD Gene:50801 KCNK4
dbSNP Gene:50801 KCNK4
ENSEMBL:ENSG00000182450 KCNK4
ENSEMBL_homo_sapiens_GENE:ENSG00000182450.14 KCNK4
HGNC:6279 KCNK4
KEGG Gene (Homo sapiens):50801 KCNK4
Monarch:50801 KCNK4
NCBI Gene:50801 KCNK4
OMIM:605720 KCNK4
UCSC:Q9NYG8 KCNK4
Reference Transcript
RefSeq:NM_001317090.1 KCNK4
RefSeq:NM_033310.2 KCNK4
Other Identifiers
11742271_s_at
11751693_s_at
11752800_s_at
16726399
16726416
224552_PM_s_at
224552_s_at
3334447
3334448
3334449
3334450
3334451
3334452
3334453
3334454
3334456
3334458
3334460
3334461
3334462
3334463
3334466
3334467
3334468
3334469
3334470
3334471
3334472
50801
7940971
A_32_P805871
A_33_P3213792
GO:0005215
GO:0005267
GO:0005515
GO:0005886
GO:0006811
GO:0006813
GO:0007613
GO:0015271
GO:0016020
GO:0019233
GO:0022841
GO:0030322
GO:0034220
GO:0034702
GO:0034705
GO:0042802
GO:0050877
GO:0050951
GO:0050976
GO:0055085
GO:0071260
GO:0071398
GO:0071469
GO:0071502
GO:0071805
GO:0097604
GO:0098782
HMNXSV003008999
ILMN_1680212
ILMN_1686791
ILMN_1721027
ILMN_1801467
TC11000594.hg
g11139499_3p_a_at
Participates
as a member of
TREK members [plasma membrane] (Homo sapiens)
as a component of
KCNK4 dimer [plasma membrane] (Homo sapiens)
Inferred To
KCNK4 [plasma membrane]
(Bos taurus)
KCNK4 [plasma membrane]
(Canis familiaris)
KCNK4 [plasma membrane]
(Sus scrofa)
TOK1 [plasma membrane]
(Saccharomyces cerevisiae)
kcnk4 [plasma membrane]
(Xenopus tropicalis)
Kcnk4 [plasma membrane]
(Mus musculus)
Kcnk4 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_201567.1
,
NP_001304019.1
Guide to Pharmacology - Targets
516
OpenTargets
ENSG00000182450
HPA
ENSG00000182450-KCNK4
GeneCards
Q9NYG8
Ensembl
ENSG00000182450
,
ENST00000394525
,
ENSP00000512851
,
ENSP00000378033
,
ENST00000539216
,
ENST00000422670
,
ENSP00000444948
,
ENSP00000402797
,
ENST00000696753
PRO
Q9NYG8
Pharos - Targets
Q9NYG8
Orphanet
29145
PDB
7LJ5
,
7LJ4
,
3UM7
,
4WFF
,
4WFH
,
7LJB
,
4WFE
,
4RUE
,
7LJA
,
4WFG
,
4RUF
,
4I9W
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